Sarsha Wilson publishes her debut blog about a recent RCT on the efficacy, safety and tolerability of augmentation pharmacotherapy with aripiprazole for treatment-resistant depression in later life.
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Data from a cohort of children (6-11 years old) participating in the Canadian Health Measures Survey (CHMS) suggests an association between vitamin D status and dental caries. Children with 25(OH)D concentrations ≥75 nmol/L had a 39% lower odds of having experienced caries.
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15 studies involving 1722 patients were included in this Cochrane review update on orthodontic retention. However, there was insufficient high quality evidence to make recommendations on retention procedures.
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Ian Hamilton presents his debut blog on a recent prospective cohort study on the relationship between teenage cannabis use, IQ and educational attainment.
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Clarissa Giebel presents the findings of a small RCT that evaluates the impact of a social work care coordination intervention on hospital readmissions in older adults.
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This small trial of probiotics as an adjunct to toothbrushing with a fluoride toothpaste to reduce caries in pre-school children suggests some additional benefit. Further studies are needed to clarify the findings, assess dose response, acceptability and cost effectiveness.
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This review of the effect of soft denture liners on masticatory function includes just 6 small studies. This is a suggestion that use of long-term silicone liners may improve mastication parameters but it is very weak.
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Nick Burton reviews a US study of people with learning disabilities living in community group homes, who help show how well they engage in meaningful social and non-social activities.
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John Baker looks at the implications of the leaked NICE review on #SafeStaffing for Nursing in Inpatient Mental Health Settings, which was recently uncovered by HSJ journalist Shaun Lintern.
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This Cochrane review update included 8 trials involving 1746 participants. Some low-quality evidence suggesting the superiority of resin-based fissure sealants over fluoride varnish applications was identified
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