A statistically significant, but small, increased relative risk of learning disabilities in children born via IVF

shutterstock_130308110

In-vitro fertilisation (IVF) is used to help people who experience difficulties in conceiving (see NICE’s guideline for information eligibility). It involves fertilising an egg with sperm in the laboratory, before reimplanting the fertilised egg into the woman’s womb to develop as normal. In cases of male infertility, the sperm can be injected directly in to [read the full story…]

Cohort study links early exposure to intimate partner violence with poor mental health outcomes, but longer follow-up is needed

family fighting

Negative childhood experiences have always been a big topic in psychology and psychiatry, as they tend to be associated with poor mental health outcomes in later life. Intimate partner violence (IPV) harms not only the adults directly involved in it, but also the children – witnessing IPV as a child is a known risk factor [read the full story…]

Identifying risk factors in first episode psychosis: results from two new meta-analyses

shutterstock_129941402

A first episode of psychosis is a higher risk time for acts of self-harm and of violence, and a chance to engage people, modify risk factors and change outcomes. Two related meta-analyses by Large, Neilssen and Challis are presented in a letter in the Australian and New Zealand Journal of Psychiatry.  They summarise two studies [read the full story…]

Review suggests that radiotherapy was associated with higher rates of implant loss

shutterstock_34428667

Implant–supported restorations show good success rates in healthy tissues while studies in irradiated jaws contrasting outcomes have been reported. The aim of this review was 
to assess the survival rate of titanium implants placed in irradiated jaws. The Medline, Embase, and CENTRAL, and  OpenGRAY databases were searched together with a number of journals (Clinical Implant [read the full story…]

Common antidepressants associated with increased risk of postpartum haemorrhage

shutterstock_18257986

Postpartum haemorrhages are serious birth complications that represent one of the leading causes of maternal mortality and morbidity. While incidences of postpartum haemorrhages have risen steadily in the past decades (in the US alone, numbers increased from 2.3% to 2.9% from 1994 to 2006), there is little evidence as to why. Antidepressants – especially selective [read the full story…]

Study shows that tooth wear was present in around 30% of young European adults

shutterstock_29993440

There is increasing interest in the levels of tooth wear being seen with a recent systematic review suggesting that between 10-30% of children have signs of established wear ( Dental Elf Sept 2011) .  The aim of this study was to determine prevalence of tooth wear on the oral and facial surfaces in 18– 35 year [read the full story…]

It’s not the combat, maybe it’s the drinking in vulnerable young men

shutterstock_82008286

A cohort study published in JAMA tried to answer the question what are the risk factors for suicide in the US military. This is a hot topic as the rate of suicide has increased in US military personnel from about 11/100,000 people in 2005 to about 18/100,000 so that now deaths from suicide outnumber deaths [read the full story…]

Tricyclic antidepressants are associated with higher risk of bone fracture

shutterstock_79304863

While most people would likely associate tricyclic antidepressants (TCAs) with more common adverse effects such as dry mouth, sedation and constipation, there is some evidence to suggest increased occurrence of bone fractures (Vestergaard, Rejnmark, & Mosekilde, 2006). However, the topic remains controversial and conflicting results about the association of TCAs and fracture risk abound (e.g. [read the full story…]

ADHD in childhood is not linked to later development of bipolar disorder

Child sitting under a tree

Bipolar disorder is considered a hereditary condition. There is emerging evidence that prodromes/early symptoms are evident in children before disorders develop. This potentially offers a chance to treat and prevent the development of mental health problems in adulthood. Being able to identifying early symptoms of the onset of this mental health disorder is clearly important, however, [read the full story…]

Maternal antidepressant use in pregnancy may be associated with a small increased risk of autism

Pregnant woman with drugs

The prevalence of autistic spectrum disorders has risen dramatically in the last thirty years, with recent estimates suggesting that 1 in 88 children in the United States have an autistic spectrum disorder. This increasing prevalence could simply be due to changes in the diagnosis of such disorders and so be of little interest. However, there [read the full story…]