Ben Janaway explores a recent review in JAMA Psychiatry on the emerging clinical neuroscience of Autism Spectrum Disorder.
[read the full story...]What causes Autistic Spectrum Disorder?
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Emotional symptoms in adolescent girls: what can we learn from the functional connectivity of neural pathways?
Shubhangi Karmaker on a recent resting-state fMRI study that explores neural network disturbances that underpin the emergence of emotional symptoms in adolescent girls.
[read the full story...]Resilience to depression: neural markers in adolescent at-risk females
Matthew Broome appraises a recent cohort study that looks at neural markers of resilience in young women at familial risk for major depressive disorder.
[read the full story...]MRI in first episode psychosis
Dan Joyce publishes his debut blog on a recent paper in the British Journal of Psychiatry that considers the feasibility and clinical utility of magnetic resonance imaging in first-episode psychosis.
[read the full story...]CBTp changes the brain’s wiring? Extraordinary claims, ordinary evidence
Keith Laws and Samei Huda are not impressed by a study on brain connectivity changes following CBT for psychosis, which received a significant amount of press coverage when it was published back in January.
[read the full story...]Microglial activity in psychosis and schizophrenia
Samei Huda summarises a small PET brain imaging study, which looks at two cohorts (Ultra High Risk of Psychosis v Controls and Schizophrenia v Controls) to compare relative levels of microglial activity.
[read the full story...]Placebo responding and µ-opioid brain functioning predict efficiency of antidepressants
Dan-Mikael Ellingsen explores the neurochemistry of placebo effects in major depression, as he reviews a recent study of the association between placebo-activated neural systems and antidepressant responses.
[read the full story...]Imaging genomics: can we link genes to brain structure and function?
Linking brain scans with genetic information offers a powerful way to further our understanding of how the brain works, but to do this properly many researchers from around the world need to collaborate. Fortunately, the ENIGMA Consortium are leading the way in this emerging field of imaging genomics.
[read the full story...]Antidepressants work by changing emotional processing
For people who are suffering from a severe depression, antidepressants are a very effective treatment, but how they work is still not fully understood. The basic biochemistry of how one dose of the drug affects one part of the nervous system is known, e.g. increasing serotonin levels at the synapse by preventing it from being [read the full story…]
Super Mario changes your brain
Some of the elves in our neck of the woods like to go on a trip to Mushroom Kingdom from time to time, just to relax and boost their abilities you understand. Unfortunately being able to double in size or become invincible hasn’t happened in real life yet, but a recent study has looked at [read the full story…]