Do antipsychotics cause progressive brain changes in schizophrenia?

People with schizophrenia taking antipsychotics saw a reduction in grey matter

For over 30 years researchers have found that people with a diagnosis of schizophrenia have, on average, differences on brain scans compared to people without.  Not everybody with a diagnosis of schizophrenia will have these differences and it has not yet been possible to use brain scanning as a test to work out whether someone [read the full story…]

Can brain imaging help predict who will respond to CBT versus antidepressants?

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A major challenge in the treatment of depression is that only a proportion of people respond to the first treatment they try.  For example, with antidepressants only 40% of people will see their symptoms fall to a level that can be considered a recovery.  Trying further treatments after the first one does not work can [read the full story…]

Brain imaging suggests that differences in emotional processing are present before developing depression

Three generations of women

When trying to understand more about about mental health problems one of the big questions is: are the results of a study due to how the person is currently feeling or are the results due to a predisposition to how they are feeling now? While often the answer will be a bit of both, researchers [read the full story…]

Can functional brain imaging of social judgments shed light on the gender imbalance in autism spectrum disorder?

social cognition

It is well-documented that there are gender differences in mental health (see for example this Men’s Health Forum publication (PDF) about key mental health issues affecting men). In early development, boys are at a significantly higher risk than girls for meeting diagnostic criteria for autism spectrum disorder (ASD), as well as other developmental problems (e.g. developmental [read the full story…]

Brain imaging reveals different pattern of activity in ADHD, which is partly normalised by medication

An image of a brain

How brain imaging can help us understand mental health problems and their treatment is another service that the mental elf team will hopefully be able to offer.  By blogging about interesting new studies we hope to help you pick up a wee bit of how MRI, CT, EEG and MEG adds to our understanding.  While [read the full story…]