This review of whether ultrasonic irrigation results in less postoperative root canal treatment pain than conventional irrigation included 6 RCTs. The suggests less pain with ultrasonic irrigation for the first 48 hours but no difference at 72 hours.
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This large RCT involving 308 patients found that using 1.3% NaOCl was associated with less intense and less frequent post-endodontic pain than 5.25% NaOCl in mandibular molars with nonvital pulps treated in two visits.
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This review of the use of non-steroidal anti-inflammatory drugs (NSAIDs) for the management of post endodontic pain demonstrates that they do help to manage the pain.
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This review of the effect of rotary or reciprocating instruments on post-endodontic pain included 3 RCTs involving 1317 patients. There is limited evidence of any clear difference between the two techniques.
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