Depression and bipolar disorder linked to an increased risk of developing dementia, says systematic review

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Dementia and affective disorders (such as depression and bipolar disorder) are usually considered to be completely unrelated afflictions. Yet a number of recent studies have suggested that the risk of developing dementia in later life may be increased for those who have had an affective disorder. A number of systematic reviews have been undertaken to [read the full story…]

New RCT says antidepressants should not be used when treating depression in dementia

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Dementia is one of the most common and serious disorders in later life. It places a considerable burden on the health care system, individuals and especially unpaid carers. Depression is common among people with dementia and causes additional distress to affected individuals and their social circle. Research into the treatment of depression in dementia is [read the full story…]

Check out the new BITE-sized mental health summaries from the NIHR CLAHRCs

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Anyone who’s spent any time at all on the Mental Elf website, or any of the other National Elf Service sites, knows that we elves love succinct and focused summaries that are easy to read and quick to digest. It’s always a delight to see other groups publishing similar resources, so I’ve decided today to [read the full story…]

Scotland sees increase in prescribing rates for mental health drugs

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The Scottish Government have published their annual summary of prescribing statistics for mental health drugs. The report shows increases in the prescribing rates for all groups of drugs over the last 12 months. The prescribing costs of some groups of drugs have also risen (ADHD, dementia, depression) although other groups have seen a decline (insomnia [read the full story…]

Structured exercise reduces depression in older people, according to new systematic review

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Regular readers of the Mental Elf will recall the blogs (Here is the evidence for exercising if you are depressed and New Cochrane review shows that exercise helps with depression) I wrote back in June and July about the evidence for exercising if you have depression. A new systematic review was published in the British [read the full story…]

Why is it so difficult to measure the prevalence of depression in people aged 75 and over?

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A number of reviews have been published in recent years, which explore the prevalence of depression in old people. Prevalence rates vary enormously from one study to the next and so the reviews tend to report quite a wide range, typically up to 10%. Prevalence is defined as: “a measure of the proportion of people [read the full story…]

Antidepressants may be less effective in older patients with depression, according to new meta-analysis

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Following on from my post yesterday about screening tools for depression in later life, here is a new meta-analysis that explores the efficacy of antidepressants for the treatment of major depressive disorder (MDD) in patients aged ≥ 55 years. The researchers from the University of Modena and Reggio Emilia in Italy just searched PubMed for [read the full story…]

The Geriatric Depression Scale is the best screening tool for depression in older people in acute hospital settings

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Depression often occurs in later life and people in poor physical condition tend to be more susceptible than others. Older people in hospital who get depressed have poorer outcomes, so it’s important that we know how to detect depression and manage it in the acute setting. This systematic review conducted by researchers in Swansea set [read the full story…]

The safety and risks of antidepressant treatment in older people: new large UK cohort study

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The aim of this study was to establish the relative safety and balance of risks for antidepressant treatment in older people. The cohort study included 60,746 patients aged 65 years and over diagnosed with depression. The study was based in 570 general practices in the UK supplying data to the QResearch database. The study objectives [read the full story…]

Depression in later life: new clinical review from the BMJ

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This week’s British Medical Journal features a review of depression in later life. The authors bring together recent systematic reviews, meta-analyses, and randomised controlled trials to summarise best current knowledge about the diagnosis and management of patients who develop depression in later life. The review addresses the following questions: What is late life depression and [read the full story…]