Home based collaborative care reduces depression in elderly people with epilepsy

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The PEARLS Program is a team-based approach, involving counsellors, psychiatrists and medical providers, designed to reduce depressive symptoms and improve quality of life in adults with epilepsy.  It was developed by a team at the University of Washington and has been studied through two randomised controlled trials, the second of which measures the long-term benefits of [read the full story…]

Sertraline and mirtazapine do more harm than good for people with dementia and depression

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Depression is common in patients with dementia and antidepressants are widely prescribed for this population although the evidence remains limited. This randomised controlled trial conducted by researchers at the Institute of Psychiatry in London and published in the Lancet, explored the safety and efficacy of two widely-used drugs (sertraline and mirtazapine) in patients with dementia and [read the full story…]

Problem-solving therapy beats supportive therapy at reducing disability in old people with depression and executive dysfunction

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Older people who suffer from depression and executive dysfunction experience significant levels of disability and often don’t respond well to conventional drug treatments. This randomised controlled trial conducted by researchers from Weill Cornell Medical College in New York State, attempted to find out if problem-solving therapy is better than supportive therapy for reducing disability in older [read the full story…]

Oestrogen receptor variations linked with depression in later life

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The hormone oestrogen could play an important role in late-life depression, according to new research published in the August issue of the British Journal of Psychiatry. Oestrogen is best known as one of the significant hormones in reproduction. It is also believed to have a part to play in mood and mental health, because of [read the full story…]

Bright light treatment helps elderly people with non-seasonal depression

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Major depressive disorder is a prevalent and debilitating condition in elderly patients. It is accompanied by circadian rhythm disturbances associated with impaired functioning of the suprachiasmatic nucleus, the biological clock of the brain. Circadian rhythm disturbances are common in the elderly. Suprachiasmatic nucleus stimulation using bright light treatment may, therefore, improve mood, sleep, and hormonal [read the full story…]