Rosalyn Nelson presents the latest Cochrane systematic review of Rivastigmine for Alzheimer’s disease, which brings together the results of 7 industry sponsored or funded trials, and concludes that Rivastigmine may be of benefit to people with Alzheimer’s disease.
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This overview includes 39 Cochrane reviews with data from around 460 studies and about 50,000 patients providing a wealth of reliable evidence on the analgesic efficacy of single dose oral analgesics.
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This overview of adverse event rates associated with single dose oral analgesics includes data from 39 Cochrane reviews, and provides evidence that adverse events rates are generally similar with active drug and placebo.
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Meg Fluharty summarises a recently updated Cochrane systematic review about interventions for drug-using offenders with co-occurring mental illness.
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Andrew Jones summarises a recent Cochrane systematic review of interventions to increase adherence to smoking cessation medications.
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The update of a 2007 Cochrane review of parasympathomimetic drugs for dry mouth after radiotherapy did not identify an new studies. The 3 RCTs identified in the previous version provide limited evidence to support the use of pilocarpine hydrochloride in the treatment of radiation-induced xerostomia.
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This review of Tooth Mousse® (casein phosphopeptide-amorphous calcium phosphate) for caries prevention only identified 12 studies (8 RCTs). Many were of short duration and exhibited a great deal of heterogeneity; while there is some suggestion of benefit, the quality of the evidence is very low.
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This Cochrane review was only able to identify a single small RCTs of acupuncture to reduce gagging during dental treatment. This was insufficient to conclude any benefit. No evidence of other interventions was identified.
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This update of a Cochrane review, first published in 2009, did not identify any RCTs comparing the efficiency of sedation versus general anaesthesia (GA) for the provision of a dental treatment.
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The updated Cochrane review only included 1 low quality RCT. A substantive reduction in decay for primary teeth was seen equivalent to a prevented fraction of 31% but further research is likely to have an important impact on this estimate.
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