Paliperidone Palmitate is no better than Haloperidol Decanoate at preventing relapse or controlling psychotic symptoms

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Alex Langford summarises a relatively large and pragmatic study, which provides firm evidence that the newer antipsychotic, Paliperidone, is no better at preventing relapse or controlling psychotic symptoms than its decades-old comparator, Haloperidol.

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We don’t know if general health advice improves physical health for patients with serious mental illness

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For me, one of the most infuriating aspects of health care is the relegation of mental health problems, and mental health services, as secondary to physical health. There are a myriad of examples of this, from the classic stigma that people with mental health problems receive compared to those with physical health problems (fantastically illustrated [read the full story…]

A new model for schizophrenia?

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Schizophrenia is a complex disorder (or, more likely, group of disorders) that has reality distortion at its core. Efforts to establish the cause of schizophrenia have been ongoing for more than a century, and many models have come and gone in that time (not for nothing has schizophrenia been called ‘the graveyard of neuropathologists’ (Plum, [read the full story…]

Spoilt for choice? Four new Cochrane reviews on antipsychotics for schizophrenia

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Schizophrenia is a crippling condition characterised by psychotic experiences such as delusions and hallucinations. It can be hugely debilitating for the patient and their family and it can also be an enormous challenge for psychiatrists and other health and social care professionals who are responsible for providing care and support to the service user. Currently, [read the full story…]

“Psychokiller, qu’est-ce que c’est”. The risk of violent re-offending among prisoners with psychotic experiences

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In England and Wales, the Mental Health Act (1983, revised 2007) allows for the detention of individuals to hospital for a period of assessment (Section 2) or treatment (Section 3) if it is deemed that they suffer with a mental disorder of a nature or degree sufficient to warrant admission to hospital and it is necessary [read the full story…]

A strong business case exists for investing in early and community-based interventions for mental health, says report

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This report provides everything that is needed for people working in mental health services to make a business case for investing in early and community-based interventions. This includes, commissioners, practitioners, local authorities, policy-makers, providers, and social care. As part of this document, the authors have provided the evidence for the cost-effectiveness of a range of [read the full story…]

Drug treatment of refractory schizophrenia remains a major challenge, but clozapine continues to be gold standard

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Schizophrenia is a crippling condition that often (in about 20-30% of patients) shows an inadequate response to first-line antipsychotic drugs. Because it is associated with significant, often devastating reductions in quality of life, the management of refractory cases of schizophrenia represents a major challenge to psychiatry. As pharmacotherapy is the treatment of choice, stringent guidelines [read the full story…]

No support for peer support?

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In this blog, I’m going to be discussing a recent systematic review and meta-analysis of “peer support for people with serious mental illness” (Lloyd-Evans et al, 2014). It’s something of a personal (as well as an academic) interest, as I am a carer and have been involved in mutual peer support groups myself. I have given [read the full story…]

Is the Dodo finally dead?

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There’s been a lot of chatter here in the woodlands about the role of cognitive behavioural therapy (CBT) in psychosis – what do service users think of it? Can it be used in place of antipsychotics for some people? Outside of the woodlands, CBT for psychosis has also been generating a lot of attention: Does [read the full story…]

Service user perspectives on individual CBT for psychosis

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I have been procrastinating about writing this blog for a while. This is, in part, caused by hesitancy about involving myself in the CBT for psychosis (CBTp) debate. Regular readers of the Mental Elf will be aware that in recent months Jauhar and colleagues presented results of a meta-analysis that called into question the effectiveness [read the full story…]