Little evidence for antibiotic use in irreversible pulpitis

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This is the latest update of this Cochrane review of the effectiveness of antibiotics for irreversible pulpitis. Only 1 small RCTs is available which provides insufficient evidence to determine whether antibiotics reduce pain or not compared to not having antibiotics

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Wealth of reliable evidence on efficacy of single dose oral analgesics

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This overview includes 39 Cochrane reviews with data from around 460 studies and about 50,000 patients providing a wealth of reliable evidence on the analgesic efficacy of single dose oral analgesics.

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Few adverse events with single dose oral analgesics for acute postoperative pain

This overview of adverse event rates associated with single dose oral analgesics includes data from 39 Cochrane reviews, and provides evidence that adverse events rates are generally similar with active drug and placebo.

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On-demand analgesic use following root canal treatment resulted in similar pain relief but reduced consumption compared with regular prescription

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The management of pre- and post-operative pain is a key component of endodontic treatment with studies reporting that the incidence of post operative pain (flare-up) ranges from  3-58%.   Nonsteroidal anti-inflammatory drugs (NSAIDs) are the most common medication used for managing pain after root canal treatment (RoCT). The aim of this study was to compare the [read the full story…]

Ibuprofen more effective than paracetamol for postoperative pain following third molar removal

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Surgical removal of third molars is a very common procedure and postoperative pain is a major concern for patients. Non-steroidal anti-inflammatory drugs are (NSAIDs) frequently recommended to manage this pain.   Ibuprofen and paracetamol commonly used and recently a combination analgesic containing both paracetamol and ibuprofen has become available in the UK. The aim of this [read the full story…]

Currently insufficient evidence to decide if antibiotics are effective in treating irreversible pulpitis

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Irreversible pulpitis often presents as an acute and intense pain and is a frequent reason for emergency dental visits.  Treatment involves accessing the root canal of the tooth to remove the inflamed pulp (nerve) and cleaning the root canal. The aim of this review was to assess the effects of systemic antibiotics for irreversible pulpitis. [read the full story…]

Small study found that pre-operative ibuprofen improved efficacy of inferior alveolar nerve blocks

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Inferior alveolar nerve block (IANB) is a routine technique for achieving regional anaesthesia. However, it is not always successful, with inflammation being a potential cause.  The aim of this study was to evaluate the effect of preoperative oral ibuprofen (IBU) on the success of inferior alveolar nerve blocks (IANBs) with mepivacaine containing 1: 100 000 epinephrine for [read the full story…]

Probably a benefit in prescribing preoperative analgesics prior to orthodontic separator placement

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Pain is not uncommon after dental procedures. This can be linked with an increase in fear of dental procedures and the possible avoidance of treatment. This is of particular importance in children and adolescents and the use of pre-operative analgesics had been suggested as a way of reducing peri-operative pain. The aim of this Cochrane [read the full story…]

Taking ibuprofen before wisdom tooth removal does not appear to be more effective for controlling post operative pain

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The removal of lower third molars is one of the commonest surgical procedures. The effective management of post operative pain is an important consideration and it has been suggested that preoperative administration of non-steroidal anti-inflammatory drugs (NSAIDs) may be more effective than post operative administration. The aim of this study was therefore to compare the [read the full story…]