Psychiatric disorders are highly heritable, but are the genes we identify in GWAS the same ones our medications target? This new study digs into the overlap and raises questions about how we develop treatments.
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This review of the prevalence of autoimmune disorders in patients with oral lichen planus (OLP) and their magnitude of association included 153 studies. while links between autoimmune thyroid diseases and diabetes mellitus where shown a majority of the included studies were of low quality.
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Jonathan Monk-Cunliffe explores a recent cohort study which finds that people with inflammatory diseases such as multiple sclerosis, rheumatoid arthritis and inflammatory bowel disease are at greater risk of “personality disorder”.
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This review the prevalence of degenerative joint disease (DJD) of the temporomandibular joints included 32 studies only 6 being considered at low risk of bias. While a high prevalence of DJD was seen in patients with juvenile idiopathic arthritis and rheumatoid arthritis the findings should be viewed cautiously.
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Tracey Howe considers a systematic review examining the impact of rheumatoid arthritis on Health Related Quality of Life, measured through the SF-36.
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In this blog, Tracey Howe considers a sytematic review exploring the incidence and risk factors for falls in people with rheumatoid arthritis.
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This recent systematic reviews asks: Does periodontal treatment influence clinical and biochemical measures for rheumatoid arthritis? The answer is that there’s insufficient evidence to know.
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There is a widespread clinical presumption that people who have both major depressive disorder (MDD) and a co-morbid chronic physical illness represent a ‘double trouble’ group. This leads to the expectation that the depression prognosis for these people would be poor with increasing likelihood of recurrence. Evidence supports the view that depression is prevalent among [read the full story…]
A friend of mine is currently training to be a Yoga instructor. This got me thinking about Yoga and musculoskeletal conditions. The different Yoga poses focus on increasing the flexibility of the joints and improving postural stability through improvements in muscle strength. Yoga also aims to release the tension on muscles with the aim of [read the full story…]
With our 5×50 worldwide exercise flash-mob challenge about to start on Friday 23rd November (see earlier post) we thought we would have a look at evidence related to physical activity and exercise for people with musculoskeletal conditions. The majority of research on people with RA has focused on the effect of exercise training with benefits [read the full story…]
