Oral lichen planus and autoimmune disorders

Lichen_planusWickham's

This review of the prevalence of autoimmune disorders in patients with oral lichen planus (OLP) and their magnitude of association included 153 studies. while links between autoimmune thyroid diseases and diabetes mellitus where shown a majority of the included studies were of low quality.

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Oral examination for detecting oral cancer

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This review of the diagnostic accuracy of visual inspection compared with biopsy (gold standard) for the diagnosis or oral cancer and oral potentially malignant dissorders included 18 studies. For malignant lesions the pooled sensitivity was 88% (95%CI; 73% to 95%) and specificity 81%(95%CI; 51% to 95%).

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Top Dental Elf Blogs: Oct – Dec 2021

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Amoxicillin and metronidazole as an adjunct to full-mouth scaling and root planing, malignant transformation on oral lichen planus and toothbrushing to prevent ventilator-associated pneumonia was out most popular blogs between October to December 2021.

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Oral lichen planus and malignant transformation

Lichen_planus

This review of high quality studies of oral lichen planus malignant transformation rate included 10 observational studies. The findings found a higher level of malignant transformation in higher quality studies 2.28% (95%CI; 1.49 to 3.20) compared with reviews including lower quality studies 1.14% (0.84 to 1.49).

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Interventions for oral lichen planus

Lichen_planusWickham's

This systematic review and network meta-analysis comparing interventions for the management of oral lichen planus included 55 RCTs. While the findings suggested that topical corticosteroids may be most effective the evidence is of low to very low certainty.

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Oral lichen planus as a risk factor for peri-implant disease

Lichen_planus

In this blog Rajpal Tattar looks at a review and meta-analysis investigating the correlation between oral lichen planus and peri-implant disease. Only two small observational studies were included so the availabel evidence is very limited.

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Top Dental Elf Blogs: Apr – Jun 2020

The Dental Elf brings you daily updates of evidence-based dentistry research

Erosive tooth wear and gastro-oesophageal reflux, oral lichen planus and oro-facial manifestations of systemic lupus erythematosus were popular blogs in April, May and June of 2020.

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Photodynamic therapy for oral lichen planus

Lichen_planusWickham's

This review looked at the efficacy of photodynamic therapy (PDT) for the treatment or oral lichen lplanus (OLP) and compares PDT with steroid therapy. 16 studies were included with the findings suggesting that photodynamic therapy may offer patients with OLP improved pain relief and better efficacy compared to topical corticosteroids.

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Human Papilloma Virus in oral potentially malignant disorders

Human Papilloma Virus

In this blog Manás Dave looks at a review of the prevalence of human papilloma virus (HPV) in oral potentially malignant disorders (OPMD). Although 52 studies were included one in five OPMDs being HPV positive is not a substantial link so teh findings need to be interpreted cautiously.

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