Oral lichen planus: malignant transformation rate

Lichen_planusWickham's

This review of the malignant transformation rate of oral lichen planus and associated risk factors included 33 studies. Using a strict definition the authors found a malignant transformation rate of 0.44%.

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Oral Lichen Planus: Is treatment with corticosteroids safe and effective?

Lichen_planusWickham's

This Cochrane review of the efficacy and safety of corticosteroids for the treatment of people with oral lichen planus(OLP) included 35 RCTs suggesting that they may be more effective than placebo for reducing the pain of symptomatic OLP but the reliability of the finding is low.

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Top Dental Elf Blogs: May – Aug 2018

The elves have been mining the archive for research blogs to support CQC's recommendations on high-quality adult social care services and support.

Popular Dental Elf blogs in May-Jun 2018 include; tooth whitening; oral surgery and anticoagulants, anxiety management in children using CBT and oral lichen planus

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Oral lichen planus and diabetes: are they associated?

Lichen_planusWickham's

This review of the relationship between oral lichen planus and diabetes included 22 studies. While both meta-analysis suggest a relationship the confidence intervals cross the line of no effect so are not statistically significant.

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Oral lichen planus: Rate of malignant transformation

Lichen_planusWickham's

This review of the malignant transformation rate (TR) of oral lichen planus included 21 observational studies the majority of which were retrospective. The overall estimate of TR was 1.4%.

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Oral potentially malignant disorders – how common are they?

Leukoplakia02-04-06

This review of the prevalence of oral potentially malignant disorders included 22 observational studies providing a pooled estimate for prevalence of 4.47% (95% CI;2.43-7.08).

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Photodynamic therapy for oral lichen planus?

iStock_000001604217XSmall dental laser

This review of photodynamic therapy (PDT) for management of symptomatic of oral lichen planus included 5 small studies of limited quality that suggest PDT may be beneficial.

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Hepatitis C and oral lichen planus

HCV

This review of the association between hepatitis C virus (HCV) and oral lichen planus (OLP) identified 19 case-controlled studies. While a 6-fold increase in risk of HCV infection was noted in OLP patients a majority of the studies took place in areas with high endemic HCV rates and there is some concern regarding publication bias and the quality of the available studies.

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Laser therapy for oral lichen planus

Lichen_planusWickham's

This review comparing low level laser therapy (LLLT) with steroids for the treatment of oral lichen planus only identified 5 studies none of which were at low risk of bias. Further high quality trials are needed to assess the efficacy of LLLT.

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Study finds better oral hygiene improved oral lichen planus

shutterstock_274582559

This small randomised trial found improvements in quality of life for patients with oral lichen planus at both 4 weeks and 20 weeks following implementation of a structured oral hygiene instruction.

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