Trauma and psychotic symptoms: clear association, but do we really understand why?


#UCLJournalClub students worked collaboratively on this blog, which appraises and summarises a recent cross sectional study looking at the psychological mechanisms that mediate effects between trauma and psychotic symptoms.

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Lithium for bipolar disorder: the best maintenance mood stabiliser protection against self-harm and suicide?


Michael Ostacher provides a robust appraisal of a recent UK cohort study that suggests bipolar disorder patients taking lithium had reduced self-harm and unintentional injury rates, when compared with patients taking valproate, olanzapine or quetiapine.

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Varenicline is not associated with an increased risk of suicide or criminal behaviour

Champix Varenicline

Abi Rose summarises a recent cohort study, which concludes that the smoking cessation drug varenicline is not associated with increased risk of suicidal or criminal behaviour, and association with psychiatric disorders are likely due to other factors.  

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Approximately 1 in 6 children develop PTSD after trauma exposure


How many children develop Post Traumatic Stress Disorder (PTSD) after a traumatic experience such as an assault, a car crash, war or disaster? William Yule, one of the godfathers of child traumatic stress research, once pointed out that rates reported in separate studies varied from 0 to 100%. So what is on average the rate [read the full story…]

CBT and other psychotherapies can help children with PTSD in the short-term, but more evidence is needed according to Cochrane


Nearly a year ago I blogged about a promising but small RCT, which showed that Trauma-focused cognitive behavioural therapy may help young children with post traumatic stress disorder (PTSD). The blog generated a fair bit of feedback from readers and so I’ve been on the look out ever since for a systematic review that brings [read the full story…]

Cannabis consumption doubles the risk of serious motor vehicle accidents


Cannabis (marijuana) is the most widely used illicit drug in the world and reports of driving under the influence of cannabis have risen in recent years. A research team from Dalhousie University in Canada conducted a systematic search and identified observational epidemiology studies of motor vehicle collisions with an appropriate control group. They included studies [read the full story…]