Oral submucous fibrosis: Is treatment with hyaluronidase and corticosteroids effective?

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This review of the efficacy of hyaluronidase combined with corticosteroids in the management of oral submucous fibrosis (OSF)included 6 small RCTs of short duration. Only one of the RCTs was considered to be at low risk of bias so additional well conducted and reported studies with larger sample are needed to evaluate treatments for OSF.

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Aloe vera for treatment of oral submucous fibrosis?

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This review effectiveness of aloe vera on alleviating the symptoms of oral submucous fibrosis included 6 RCTs . The findings suggest a possible benefit but 5 of the trials were at high risk of bias so the findings should be viewed cautiously.

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Little evidence for drug treatments for oral submucous fibrosis

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Oral Submucous fibrosis (OSMF) is a chronic disease caused by the use of areca nut. It  is associated with significant morbidity (including pain and reduced oral opening) and an increased risk for malignancy. The aim of this review identify the published literature on the role of various drugs in the treatment of oral submucous fibrosis. [read the full story…]