Adding mannitol improved the effectiveness of local anaesthesia

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Modern local anaesthetics have transformed the practice of dentistry. However  a proportion of  injections fail to achieve pulpal anaesthesia.   This trial set out to find if  the addition of mannitol to lidocaine with epinephrine improved its efficacy. Forty patients were randomised to receive  an inferior alveolar nerve (IAN) block  in 3 separate appointments spaced at [read the full story…]