16 low quality RCTs were included in this review of the effect of calcium hydroxide lining on clinical success in treatment of deep carious lesions. 6 RCTs contributed to the meta-analysis suggesting no beneficial effect.
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Seven RCTs were included in this review of of micro-invasive interventions for non-cavitated proximal caries suggesting that resin infiltration is effective in arresting caries progression.
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3 small trials were identified for this Cochrane review of adhesives for fixed orthodontic brackets
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This review of composite resin or glass ionomer cement for Class II restorations in primary molars included 10 RCTSs finding similar clinical performance.
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15 RCTs were included in this Cochrane review of Atraumatic Restorative Treatment (ART) comparing with conventional treatment for managing dental caries lesions in the primary and permanent teeth provided low quality evidence that ART using H-GIC may have a higher risk of restoration failure in primary teeth.
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38 trials were included in this updated Cochrane review of the effect of fissure sealants on occlusal caries. The data show a reduction in caries of between 11-51% at 24months compared to no sealant. The benefit was also maintained at longer-term follow up.
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This small but well conducted RCT compares the effectiveness of MTA and calcium hydroxide for direct pulp capping material in adult molars with carious pulpal exposure finding better performance for MTA at 3 years.
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The Cochrane review of of materials for retrograde root filling identified 6 RCTs all at high risk of bias. The trials provide insufficient evidence to draw any conclusion as to the benefits of any one material over another so more high quality studies are needed.
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This Cochrane review update included 8 trials involving 1746 participants. Some low-quality evidence suggesting the superiority of resin-based fissure sealants over fluoride varnish applications was identified
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This review included 13 small studies of limited quality. While the available evidence suggests there may be no difference, further long-term high quality studies are required to confirm if this is the case.
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