Toothpaste: Does it inhibit plaque regrowth?


This review of the effect of a regular fluoride dentifrice compared to water or saline on dental plaque inhibition using the 4-day non-brushing model included 9 studies and demonstrated a weak weak inhibitory effect on plaque regrowth with toothpaste use.

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Whitening toothpastes have beneficial effect on staining

shutterstock_26227375 toothbrushes and toothpaste

This review of the effect of whitening toothpastes on tooth staining included 21 RCTs and found a significant effect on all aspects of staining in the short term.

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Anti-plaque agents: do they help reduce plaque levels?


63 RCTs contributed to this network meta-analysis of the effectiveness of anti-plaque agents. Results suggested that toothpastes containing triclosan-copolymer or chlorhexidine and mouthrinses containing essential oils or chlorhexidine had the most effect on plaque indicies at 6 months.

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Toothpaste and plaque removal

Plaque off, Fluoride on. Brushing your teeth really is that simple.
Image: Adam Drewes (CC BY-NC-SA 2.0)

This review of the efficacy of brushing with and without a toothpaste for plaque removal identified 10 trials involving a total of 444 patients. While the results suggest no differences other reviews have demonstrated clear oral health benefits from brushing with toothpaste.

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Arginine in combination with calcium bases and fluoride in toothpaste may be better than fluoride alone


Ten trials were included in this review of arginine in toothpaste. It found that arginine in combination with calcium bases (either Dical or calcium carbonate) and fluoride provided a superior effect compared with fluoride alone. However, 9 out of 10 of the trials were sponsored by a single company and the overall quality of the evidence was considered to be low.

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Mouthwashes and toothpastes can improve oral malodour


This review identified 12 trials of mouthwashes and toothpastes for oral malodour. Those products with active ingredients reduced oral malodour but the overall quality of the available evidence was weak.

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Root caries: review suggests potential benefits from 5000ppm fluoride, chlorhexidine and silver diamine varnishes


The prevalence of root caries is expected to rise and this review looked at a range of agents for non-invasive management. While 30 studies were identified they consider a large number of agents. While the review suggested that 5000ppm fluoride dentifrice was effective the number of available trials for this and the other agent was small and of limited quality.

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Review found little short-term differences in gingival condition between triclosan-containing and stannous fluoride toothpastes


While there have been reductions in caries prevalence in many countries ,levels  of gingivitis remain high. Toothpastes aid tooth cleaning and provide a useful delivery agent for plaque control agents. The aim of this review was to compare the effectiveness of stannous fluoride (SnF) toothpastes with triclosan-containing (Tcs) toothpastes in improving gingival inflammation and plaque [read the full story…]

Chlorhexidine mouthwash better than chlorhexidine dentifrice or gel at inhibiting plaque but it leads to more tooth discolouration

shutterstock_20760106 - mouthwash

The role of chlorhexidine (CHX) in inhibiting plaque growth has been extensively studied. The aim of the review was to evaluate the effectiveness of CHX-containing dentifrice (DF) or gel (CHX DF/gel) compared with CHX mouthwash (MW). Searches were conducted in Medline-PubMed, the Cochrane Central Register of Controlled Trials (CENTRAL) and Embase databases. Randomized controlled trials [read the full story…]

Review suggests that brushing with a chlorhexidine-containing dentifrice may help control plaque and gingivitis


Regular and effective removal plaque is considered to be an efective method of controlling and preventing gingivitis. Toothbrushing with dentifrice is a key method and antiplaque agents (eg chlorhexidine, triclosan/copolymer) have been introduced with the aim of increasing effectiveness.   The aim of this review was to see if chlorhexidine (CHX) dentifrice /gel was more effective [read the full story…]