Cochrane review finds no good quality evidence for common medicines used to treat sleep problems in Alzheimer’s Disease


People with dementia caused by Alzheimer’s Disease (ADD) (which is estimated to be around three quarters of people with dementia) often suffer from sleep disturbances.  These symptoms cause distress to the person with dementia and to their carers, increase the likelihood of admission to a care home, and are also very difficult for care home [read the full story…]

ADHD and the importance of healthy sleep

child sleeping on school books

Good sleep is a crucial part of our physical and mental well-being. We typically spend about a third of our lives asleep but when we miss out on sleep, we can feel fatigued and struggle to concentrate. Sleep problems are generally quite common and have been reported as one of the most common health conditions [read the full story…]

NICE evidence summary on the unlicensed and off-label use of melatonin for sleep disorders in children with ADHD


NICE have recently started publishing a series of evidence summaries looking at unlicensed and off-label medicines. The second summary in the series looks at the use of prolonged-release melatonin tablets as a treatment for sleep disorders in children and young people with attention deficit hyperactivity disorder (ADHD). Future mental health summaries include ‘Quetiapine for generalised [read the full story…]

Melatonin administration in autism spectrum disorder improved sleep parameters, daytime behaviour and had minimal side effects


The researchers in this review looked at findings related to melatonin in autism spectrum disorders (ASD), including autistic disorder, Asperger syndrome, Rett syndrome, and pervasive developmental disorders, not otherwise specified. From a search of databases, they were able to find 35 studies that met review’s inclusion criteria. It was possible to perform a meta-analysis on [read the full story…]