Caries prevention in young children: topical fluoride alone not sufficient suggests trial

caries upper arch

This large trial investigated the use of a ‘preventive package’ of fluoride varnish, fluoride toothpaste, toothbrush and standard dental health education in children between 2-3 years attending general practice. The intervention did not keep young children caries free but did reduce caries levels.

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White spot lesions: available treatments may provide improvements

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This review of treatments for post orthodontic white spot lesions included 20 studies examining a wide variety of approaches. Modest benefits were seen in addition to daily use of fluoride toothpaste and furhter high quality studies are needed to identify the best approaches.

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Toothpaste and plaque removal

Plaque off, Fluoride on. Brushing your teeth really is that simple.
Image: Adam Drewes (CC BY-NC-SA 2.0)

This review of the efficacy of brushing with and without a toothpaste for plaque removal identified 10 trials involving a total of 444 patients. While the results suggest no differences other reviews have demonstrated clear oral health benefits from brushing with toothpaste.

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Arginine and caries prevention

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7 RCTs were included in this review of the caries prevention effects of arginine containing dental products. They provide insufficient evidence to support a caries preventive effect for arginine in toothpaste.

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Arginine in combination with calcium bases and fluoride in toothpaste may be better than fluoride alone

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Ten trials were included in this review of arginine in toothpaste. It found that arginine in combination with calcium bases (either Dical or calcium carbonate) and fluoride provided a superior effect compared with fluoride alone. However, 9 out of 10 of the trials were sponsored by a single company and the overall quality of the evidence was considered to be low.

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Xylitol in toothpaste may provide small additional benefit over fluoride toothpastes

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This Cochrane review included 10 studies and found low quality evidence that fluoride toothpaste containing xylitol may be more effective than fluoride-only toothpaste for preventing caries in the permanent teeth. The evidence for other xylitol products is insufficient to assess effectiveness.

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Root caries: review suggests potential benefits from 5000ppm fluoride, chlorhexidine and silver diamine varnishes

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The prevalence of root caries is expected to rise and this review looked at a range of agents for non-invasive management. While 30 studies were identified they consider a large number of agents. While the review suggested that 5000ppm fluoride dentifrice was effective the number of available trials for this and the other agent was small and of limited quality.

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Study finds that high-fluoride toothpaste can reduce white lesions around orthodontic brackets

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Failure to maintain good oral hygiene during fixed appliance orthodontic treatment can lead to the development of demineralised white lesions (DWLs) around the orthodontic brackets.  The incidence of this adverse effect of treatment has bee reported as being between 15-85.  A recent Cochrane review by Benson et al (see Dental Elf 27th Jan 2014) found [read the full story…]

Study suggests that dentifrices containing 1.5% arginine, an insoluble calcium compound provides additional benefit to fluoridated toothpastes

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Cochrane reviews have clearly documented the anti-caries benefits of fluoridated toothpastes (Marhino et al 2003, Walsh et al 2010). New agents to improve caries prevention would assist efforts to reduce the impact of caries, particularly on children. The aim of this study was to investigate the efficacy of two dentifrices containing 1.5% arginine, an insoluble [read the full story…]

Use of higher concentration fluoride toothpaste (5000 ppm F) had a beneficial effect on root caries

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The aim of this clinical trial was to test the effectiveness of high-fluoride toothpaste (5000 ppm F) on root caries lesions in adults and to test the hypothesis that high concentration fluoride tooth- paste would effectively improve the surface hard- ness in root caries lesions in adult patients. Adult patients (18-75yrs) with 10 or more [read the full story…]