Bruxism in Down Syndrome patients


This review to assess the prevalence in bruxism in patients with Down Syndrome included 8 small studies. The studies were hetrogeneous with a pooled prevalence of 33% (95% CI: 22 to 45%).

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Periodontal treatment and prevention in Down syndrome patients


Only 9 small studies were identified for this review of the prevention and treatment of periodontal disease in patients with Down’s syndrome. More high quality studies are needed to help inform clinical practice

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Psychiatric illnesses and some chronic physical illnesses are associated with an increased risk of self-harm and suicide


Last month, the Department of Health published the ‘Closing the Gap’ report, which highlighted the importance of better integration of physical and mental health care at every level. The report specifically flagged up the need for frontline services to respond better to people who self-harm, and cited statistics that emphasise the cyclical nature of the [read the full story…]

Memantine is not an effective treatment for dementia in people with Down’s syndrome, according to new RCT


People with Down’s syndrome are more likely to develop dementia than others and one in three will have the illness as early as in their 50s. Despite this high prevalence, there is very little reliable research about drug treatments for this population. This small randomised controlled trial (funded by the drug company Lundbeck) aimed to [read the full story…]