A PACE-gate or an editorial without perspectives?


This commentary by Kjetil Gundro Brurberg, Signe Flottorp and Aase Aamland was written in response to an invitation from the Editor of the Journal of Health Psychology, who subsequently decided not to publish it. In the interest of science and open debate, we have decided to publish the commentary.

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The PACE Trial for chronic fatigue syndrome: choppy seas but a prosperous voyage


Simon Wessely responds to the huge amount of recent criticism that has surrounded the publication of a follow-up paper of the PACE trial into chronic fatigue syndrome. This extended blog presents the PACE trial and its main results, but also reminds us what makes a good RCT, as well as exploring how well PACE measures up.

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Exercise therapy for chronic fatigue syndrome


In this blog, Tracey Howe looks at a Cochrane systematic review, examining the effects of exercise therapy for patients with Chronic Fatigue Syndrome.

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Online CBT is an effective treatment for chronic fatigue syndrome in adolescents, according to small RCT


Existing trials have shown that cognitive behavioural therapy is a promising treatment for chronic fatigue syndrome. The availability of CBT is patchy, so there is an increasing body of research investigating whether internet-based treatment is a viable alternative. A new small randomised controlled trial conducted by researchers from the Netherlands has been published in the [read the full story…]