Folic acid for depression: results of the FolATED study

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Susie Johnson reports on the FolATED RCT and economic evaluation of folic acid for depression. The study finds no evidence that folic acid is clinically effective or cost-effective in augmenting antidepressants and speculates instead that methylfolate may be a better candidate for future research.

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Are treatments for borderline personality disorder cost-effective?

Dialectical behaviour therapy was specifically developed to help people with borderline personality disorders

Our resident Elf Economist, Chris Sampson, reports on a new systematic review of economic evaluations for borderline personality disorder. Are any cost-effective?

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Are treatments for bipolar disorder cost-effective?

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Chris Sampson reports on a recent systematic review and critical appraisal of economic evaluations in bipolar disorder. He finds that there’s a pressing need for new studies, especially discrete event simulations.

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Cytisine and varenicline for smoking cessation

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Andrew Jones and Chris Sampson report on a systematic review and economic evaluation of cytisine and varenicline for smoking cessation, which finds that both drugs are clinically effective compared with placebo.

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CBT in primary care is cost-effective for treatment-resistant depression

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Elf economist Chris Sampson reports on the economic evaluation of the CoBalT RCT, which finds that CBT is cost-effective for treatment resistant depression in primary care.

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Joint crisis plans: cost-effective for whom?

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Chris Sampson looks at the economic outcomes of a recent RCT of joint crisis plans to reduce compulsory treatment for people with psychosis. The study reports the potential for gains specifically among Black patients.

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Health effects of depression: keeping economists’ models on track

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Health Economist Christopher Sampson reports on a recent systematic review and meta-analysis, which shows health-related quality of life utility values vary between studies and economic models should consider this.

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It may not be possible to generate clear-cut evidence on integrated care, reports a new evidence summary

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This recent report, commissioned by the European Commission and compiled by RAND Europe, aims to summarise economic evaluation evidence on the impact of integrated care.  The authors restricted their evidence search to systematic reviews and meta analyses, which is understandable as this is described as a rapid review but the authors acknowledge this has limitations, [read the full story…]

Is telephone peer support for the prevention of postnatal depression worth the cost?

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. Peer support has been a hot topic in the woodland recently. Although there appears to be a lack of evidence to support the clinical effectiveness of peer support interventions for people with severe mental illness, such as bipolar disorder and schizophrenia, it is an approach that is highly valued by many. It might be [read the full story…]

Is treatment for depression cost-effective in people with diabetes?

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There is evidence to suggest that people with diabetes are twice as likely to suffer from depression. It’s therefore important that the cost-effectiveness of treatments for comorbid depression be indentified. The elves have already reported on a review of the effectiveness of collaborative care for people with diabetes and depression, suggesting that the intervention might be effective. While [read the full story…]