Oral Cancer diagnosis: biopsy and histology still best method

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This Cochrane review of adjunctive diagnostic tests for oral cancer included 41 studies assessing vital staining, cytology, and light-based tests. The available studies were of poor quality detection with none of the tests being considered as a replacement for the currently used standard of a scalpel biopsy and histological assessment.

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Oral cancer detection: Limited evidence for use of chemiluminescence and autofluorescent imaging devices in primary care

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Early detection of oral cancer improves prognosis so methods to improve diagnosis are welcome. The review we look at today looks at two light-based systems: chemiluminescence or autofluorescence. 25 studies were included and they are well summarised but few were tested in primary care. Neither system provided much improvement on the level of sensitivity and specificity achieved by conventional oral examination. Therefore it is suggested that these tools are better suited to specialist clinics in which there is a higher prevalence of disease and where experienced clinicians may better discriminate between benign and malignant lesions.

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Oral examination to detect potentially malignant disorders and mouth cancer

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November is Mouth Cancer Awareness month here in the UK and around 6,500 cases are diagnosed a year. Mouth cancer is the 6th commonest cancer worldwide.  In India, Sir Lanka and Pakistan it is the most common cancer for men and is responsible for 30% of all new cancer cases. Tobacco use, alcohol consumption, betel [read the full story…]