![soumitro-joy-1ocglf7UGvQ-unsplash](https://www.nationalelfservice.net/cms/wp-content/uploads/2021/10/soumitro-joy-1ocglf7UGvQ-unsplash-150x150.jpg)
Alexandra Pike, Alexis An Yee Low and Jonathan Roiser critically appraise a recent n-of-1 study on ‘brain pacemakers for depression’, which received extensive press coverage earlier this month. The case study looks at deep brain stimulation (closed-loop neuromodulation) in an individual with treatment-resistant depression.
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