Oral anticoagulant therapy: Preventing bleeding in patients having dental extractions


This Cochrane review of antifibrinolytic agents for preventing bleeding in people on oral anticoagulants undergoing dental extractions or minor oral surgery included 4 RCTs. Topical tranexamic acid was effective in reducing post-operative bleeding following dental procedures.

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Review shows that tranexamic acid reduced blood loss in orthognathic surgery


Significant blood loss can occur during orthognathic surgery and there are risks associated with blood transfusion so minimizing blood loss during surgery is important.  A large number of trials and reviews have shown that the antifibrinolytic agent tranexamic acid ( a synthetic amino acid lysine analog )  can effectively reduce bleeding in a number of [read the full story…]