Orthognathic surgery: intra-operative bleeding reduced with tranexamic acid


This review looked at the efficacy of haemostatic adjuncts on intra-operative blood loss in orthognathic surgery. 11 RCTs were included and found that tranexamic acid reduced blood loss by about a third whether used topically or intravenously.

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Review shows that tranexamic acid reduced blood loss in orthognathic surgery


Significant blood loss can occur during orthognathic surgery and there are risks associated with blood transfusion so minimizing blood loss during surgery is important.  A large number of trials and reviews have shown that the antifibrinolytic agent tranexamic acid ( a synthetic amino acid lysine analog )  can effectively reduce bleeding in a number of [read the full story…]