Smokers may have poorer results after periodontal treatment


This latest critical summary from the ADA-EBD Center for Evidence-Based Dentistry looks at a review by Patel et al 2011 which addresses the question  of whether smokers have poorer bone regeneration than non-smokers after periodontal treatment.

The appraiser considered this to be a well-conducted systematic review and meta-analysis that included 10 articles with 458 participants (154 smokers and 304 nonsmokers). While the original reviewers noted substantial heterogeneity the appraiser did not think that this was well handled.  The risks of publication bias were not investigated and there was limited information on the design and quality of the included and excluded studies.

While the original reviewer concluded that bone regeneration was poorer following periodontal treatment in patients who smoked the appraiser did not consider this that this conclusion was directly supported by the results.  Their overall assessment being

Results from studies with moderate to high risk of bias consistently suggest that smoking will have a negative effect on periodontal bone regeneration after periodontal treatment.


In my blog on May 3rd  a number of other reviews that have looked at smoking and periodontal outcomes were highlighted.


ADA-EBD Summary – Smokers may experience poorer bone regeneration than non-smokers after periodontal treatment

Patel RA, Wilson RF, Palmer RM. The effect of smoking on periodontal bone regeneration: a systematic review and meta-analysis. J Periodontol. 2012 Feb;83(2):143-55. doi: 10.1902/jop.2011.110130. Epub 2011 May 31. Review. PubMed  PMID: 21627463.

Dental Elf 3rd May 2013 – Limited information on the effects of smoking cessation on clinical outcomes following periodontal therapy

Share on Facebook Tweet this on Twitter Share on LinkedIn Share on Google+
Mark as read
Create a personal elf note about this blog
Profile photo of Derek Richards

Derek Richards

Derek Richards is a specialist in dental public health, Director of the Centre for Evidence-Based Dentistry and Specialist Advisor to the Scottish Dental Clinical Effectiveness Programme (SDCEP) Development Team. A former editor of the Evidence-Based Dentistry Journal and chief blogger for the Dental Elf website until December 2023. Derek has been involved with a wide range of evidence-based initiatives both nationally and internationally since 1994. Derek retired from the NHS in 2019 remaining as a part-time senior lecturer at Dundee Dental School until the end of 2023.

More posts - Website

Follow me here –