Critical summaries from the American Dental Association Center for Evidence-Based Dentistry


Two new critical summaries are now available at the ADA-EBD site

The first one is of a 2011 review by  Yengopal and Mickenautsh; The aim of the review was to assess whether resin-modified glass-ionomer cement (RM-GIC) offered a significant caries-preventive effect compared with resin-based composite (RBC)?

The appraiser generally considers the review to be well conducted although questioning the decision of studies, which evaluated restorations as well as orthodontic adhesives.  All the included studies were prospective studies although follow up period ranged from 4 weeks to 25 months.

The review included 4 studies and did not find a difference between in caries adjacent to RM-GIC and RBCs  but the available evidence was limited.  A commentary on this review by Pendrys is also available in the Journal of Evidence-based Dental Practice.


The second summary is of a 2010 review by Rogers et al  that addresses the question;  Does the use of fluoride containing orthodontic adhesives reduce decalcification in patients receiving orthodontic treatment.

The appraiser notes that although a detailed search of 5 databases was carried out and 10 studies included there was significant variation in the studies with each of the studies using a different adhesive. As a result the evidence to support an effect for fluoride containing orthodontic adhesives on decalcification was poor.   A commentary on this review by  Martinez-Mier is also available in the Journal of Evidence-based Dental Practice.


ADA-EBD  No difference in caries outcome between resin-modified glass ionomer cements and resin-based composites

Yengopal V, Mickenautsch S. Caries-preventive effect of resin-modified glass-ionomer cement (RM-GIC) versus composite resin: a quantitative systematic review. Eur Arch Paediatr Dent. 2011 Feb;12(1):5-14. Review. PubMed PMID: 21299939

Pendrys DG. Resin-modified glass-ionomer cement (RM-GIC) may provide greater caries preventive effect compared with composite resin, but high-quality studies  are needed. J Evid Based Dent Pract. 2011 Dec;11(4):180-2. PubMed PMID: 22078826

ADA-EBD Inconclusive evidence on decalcification associated with use of fluoride-containing orthodontic adhesives

Rogers S, Chadwick B, Treasure E. Fluoride-containing orthodontic adhesives and decalcification in patients with fixed appliances: a systematic review. Am J  Orthod Dentofacial Orthop. 2010 Oct;138(4):390.e1-8; discussion 390-1. Review. PubMed PMID: 20889037

 Martinez-Mier EA. Fluoride-containing orthodontic adhesives may reduce the occurrence of enamel demineralization in patients with fixed orthodontic appliances. J Evid Based Dent Pract. 2011 Sep;11(3):132-4. doi: 10.1016/j.jebdp.2011.06.016. PubMed PMID: 21855810




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Derek Richards

Derek Richards is a specialist in dental public health, Director of the Centre for Evidence-Based Dentistry and Specialist Advisor to the Scottish Dental Clinical Effectiveness Programme (SDCEP) Development Team. A former editor of the Evidence-Based Dentistry Journal and chief blogger for the Dental Elf website until December 2023. Derek has been involved with a wide range of evidence-based initiatives both nationally and internationally since 1994. Derek retired from the NHS in 2019 remaining as a part-time senior lecturer at Dundee Dental School until the end of 2023.

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