This review of the influence of different regenerative techniques and materials on the outcome of endodontic surgery includes 11 RCTs. The findings suggest that regenerative approaches improve periapical lesion healing after endodontic surgery. However the studies are small and only 2 are at low risk of bias.
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This review of the diagnostic accuracy of ultrasound in differentiating periapical lesions of endodontic origin in comparison with histopathology included 12 studies. While the findings suggest good levels of sensitifity and specificity for diagnosing periapical cysts and granulomasthere are concerns regarding the quality of the evidence.
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