This large cohort study looked at whether depression is a risk factor of temporomandibular disorder (TMD). The study used claims data from The National Health Insurance program of Taiwan which covers more than 96% of its 23 million population. From the database 7,587 patients who are newly diagnosed individuals with depression and 30,197 comparison subjects were randomly selected from a non-depression cohort. Both groups were followed from 2000-1 until the end of 2008 to measure the incidence of TMD.
- The incidence of TMD was 2.65 times higher in the depression cohort than in the non-depression cohort (6.16 versus 2.32 per 1000 person-years).
- Cox’s proportional hazard ratio (HR) of TMD for the depression cohort was 2.21 (95% CI 1.83–2.66), after controlling for socio-demographic factors and other psychiatric comorbidities.
- Women had higher risk to develop TMD than men:
- HR 1.61, 95% CI 1.36–1.92 for women without depression
- HR 3.54, 95% CI 2.81–4.45 for women with depression.
A temporal relationship between depression and TMD seems to exist. These results imply that dentists involved in the management of TMD need to be aware of the comorbidity of depression in these patients.
Liao CH, Chang CS, Chang SN, Lane HY, Lyu SY, Morisky DE, Sung FC. The risk of temporomandibular disorder in patients with depression: a population-based cohort study. Community Dent Oral Epidemiol. 2011 May 30. doi: 10.1111/j.1600-0528.2011.00621.x. [Epub ahead of print] PubMed PMID: 21623863