The latest Cochrane protocol from the Oral Health Group to be published is planning to look at the clinical effectiveness and safety of interventions in the pain, episode duration and episode frequency of oral ulcers and any change in the quality of life for patients with aphthous-type ulceration associated with Behçet’s disease.
Behçet’s disease is a chronic, relapsing, multisystem, inflammatory vasculitis that is characterised by a multitude of systemic signs and symptoms. Oral and genital ulcerations, skin lesions, uveitis, and inflammatory vascular involvement of the central nervous system and gastrointestinal tract are common.
Taylor J, Brocklehurst P, Walsh T, Riley P, Glenny AM, Gorodkin R, Pemberton MN. Interventions for the management of oral ulcers in Behçet’s disease (Protocol). Cochrane Database of Systematic Reviews 2014, Issue 3. Art. No.: CD011018. DOI: 10.1002/14651858.CD011018.