Another critical summary of a systematic review prepared under the auspices of the American Dental Association Center for Evidence-Based Dentistry. Originally published in 2010 , the review aimed to assess the frequency of non-odontogenic dentoalveolar pain six months or more after endodontic therapy.
The summariser notes the that both English and non-English language articles were included in the search. The included articles were restricted to prospective designs and although loss to follow up was a potential bias highlighted by the summariser the overall quality of evidence present was considered good.
Overall the review notes that around half of all persistent pain post endodontic therapy may be of non-odontogenic origin.