Do psychiatric disorder genes overlap with their drug targets? And does this matter?

feat

Psychiatric disorders are highly heritable, but are the genes we identify in GWAS the same ones our medications target? This new study digs into the overlap and raises questions about how we develop treatments.

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Review is positive on effectiveness of differential reinforcement but warns more robust studies are needed.

argue

Differential reinforcement (DR) is a non-aversive, reinforcement based behavioural intervention; which works by singling out a desired behaviour and reinforcing it, whilst ignoring other non desired behaviours. This literature review looked to summarize and provide a methodological analysis of studies, conducted between 1980 and 2009, using differential reinforcement to reduce problem behaviours in adults with [read the full story…]