Results: 675

For: randomised controlled trial

Turn on, tune in, drop out! Music therapy no better than usual care for young people

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Lisa Burscheidt is rather disappointed by a randomised controlled trial of music therapy for children and adolescents with behavioural and emotional problems.

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Step wise caries removal sustained pulp vitality up to 5 years

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This well designed trial compares the impact on pulp vitality of step wise verses traditional caries removal. after 5 years. THe findings suggest significantly improved outcomes with the step wise approach.

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Caries prevention in young children: topical fluoride alone not sufficient suggests trial

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This large trial investigated the use of a ‘preventive package’ of fluoride varnish, fluoride toothpaste, toothbrush and standard dental health education in children between 2-3 years attending general practice. The intervention did not keep young children caries free but did reduce caries levels.

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Occlusal caries prevention: Seal or varnish?

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This large, well-conducted study in a primary care setting found a small, but not statistically significant difference, between fissure sealants and fluoride varnish for the prevention of caries in first permanent molars at 36 months.

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Depression in later life: who benefits most from antidepressants plus exercise?

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Linda Gask explores an RCT of physical exercise for depression in later life, which considers the best way to customise the intervention for primary care.

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Exercise and iCBT for depression: how do ‘alternative’ treatments compare to usual care?

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Bethan Davies publishes her debut blog on a recent Swedish RCT of exercise and internet-based cognitive-behavioural therapy for depression.

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Diet and depression: can we eat our way out of clinical depression? The ‘SMILES’ trial

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Murtada Alsaif chews over the SMILES RCT of dietary improvement for adults with major depression, which reports encouraging results for healthy diet in people with depression.

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Targeting unhelpful repetitive negative thinking in young people to prevent anxiety and depression

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Michelle Moulds publishes her debut blog on a recent randomised controlled trial about the prevention of anxiety disorders and depression by targeting excessive worry, rumination and repetitive negative thinking in young adults.

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Collaborative care may help older adults with subthreshold depression: CASPER trial

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Ben Hannigan summarises the new CASPER trial of collaborative care versus usual care for older adults with subthreshold depression.

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Psychotherapies for depression in children and adolescents: all of equal IMPACT?

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Jasmin Wertz summarises the recently published IMPACT trial, which found that CBT, short-term psychoanalytical psychotherapy and brief psychosocial interventions (psychoeducation) were all equally effective in treating depression in children and young people.

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