This review of adjuvant antibiotics for diabetics undergoing periodontal treatment included 13 small RCTs. While a statistically significant improvement in probing depth was seen the magnitude of this improvement is unlikely to be clinically significant.
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Alan Underwood highlights a new meta-analysis, which suggests that people with mental health problems can benefit if they are prompted to form if-then plans, which specify when, where and how they will achieve their goals.
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Murtada Alsaif summarises a recent network meta-analysis, which looks at the efficacy, acceptability and tolerability of antipsychotics for treatment-resistant schizophrenia.
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Samei Huda presents the findings of a new meta-analysis, which explores the prognostic significance of competing ways of defining and measuring brief psychotic episodes.
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Sarah McDonald reports on a meta-analysis published yesterday, which found that when compared with active treatment, mindfulness-based cognitive therapy resulted in a reduced risk of depressive relapse.
This blog also features a podcast interview with the lead author of the research, Professor Willem Kuyken.
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The majority of the included studies in this review of the ferrule effect in-vitro studies ( 32 out of 37) and while they indicate greater longevity in teeth with ferrules further information is needed from clinical studies.
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This Cochrane review of Infraorbital nerve block for postoperative pain after cleft lip repair includes 8 trials providing low to very low quality evidence that infraorbital nerve block with lignocaine or bupivacaine may reduce postoperative pain more than placebo
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11 studies were identified for this review of lingual fixed orthodontic appliances. while some benefits were suggested the quality of the available studies was very low providing insufficient evidence of the effectiveness of lingual appliances.
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This review of probiotics use for caries and periodontal disease management identified 50 studies. Most focused on surrogate outcomes (bacterial counts) and the overall quality of the evidence supporting probiotic therapy was graded as very low for all outcomes.
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This review of narrow titanium–zirconium alloy (Ti–Zr) implants included 9 studies ( 2 RCTs) which suggest good survival rates (>95%) after 2 years.
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