Results: 1413

For: meta-analysis

Coffee consumption and oral cancer

Prescribing a placebo does not equate to no treatment, because the healthcare setting itself should include all kinds of supportive and therapeutic elements.

This review includes 11 case-controlled and 4 cohort studies and suggests a 37% reduction of oral cancer risk in high coffee drinkers compared with low or no coffee drinkers OR= 0.63 (95%CI; 0.52 – 0.75)

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Orthodontic treatment with fixed appliances – how long does it take?

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25 studies include 20 RCTs and 5 controlled trials were included this review. They were all conducted in a hospital or university setting and found that treatment duration was on average 19.9 months (95% CI; 19.58 to 20.22 months) over 17.81visits ( 95%CI; 19.71 to 20.32 months)

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Methylphenidate for ADHD: have Cochrane got it wrong this time?

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Chris Hollis appraises a recent Cochrane systematic review, which casts doubt over the quality of trial evidence and the clinical effectiveness of Methylphenidate for ADHD.

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Amoxicillin and metronidazole as an adjunct to scaling and root planning for periodontitis?

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This review of the adjunctive use of amoxicillin and metronidazole with scaling and root planing for the management of periodontitis found improved clinical outcomes in terms of pocket depth and clinical attachment level with their use.

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Tooth autotransplantation: review suggests good survival but evidence limited

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Only 5 small studies were included in this review of the long term outcomes of tooth autotransplantation. All but one was retrospective so the findings which suggest 81% survival at 6 years should be interpreted with caution.

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Commonly prescribed psychiatric drugs: do they work?

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John Baker summarises a review of commonly prescribed medication that covers seven psychiatric drugs, including antidepressants, antipsychotics, benzodiazepines, amphetamines, methylphenidate and cholinesterase inhibitors.

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Third molars: single dose of preoperative antibiotic reduced infection

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10 RCTs were included in this review of preoperative antibiotics for removal of third molars. The use of antibiotics significantly reduced the odds of surgical site infection or alveolar osteitis (OR = 0.30; 95% CI, 0.19 to 0.47; P≤.00001)

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Furcation involvement may double risk of tooth loss in periodontitis

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This review of the impact of furcation involvement on tooth loss in periodontal disease found 21 pro- and retrospective studies. The data suggests that the risk of tooth loss may be doubled where there is furcation involvement.

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Dental implants – immediate placement in infected sockets may increase failure rates

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This review of dental implants placed in infected sockets included 7 studies all considered to be a at high risk of bias. The findings suggest that failure rates are higher in infected sockets but the findings should be interpreted with caution.

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Transcranial magnetic stimulation for schizophrenia

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Joanne Wallace considers the findings of a new Cochrane systematic review on Transcranial Magnetic Stimulation (TMS) for schizophrenia.

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