40 cross-sectional studies involving a range or oral health related quality of life measures were included in this review. They found that malocclusion has a small impact on oral health related quality of life.
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Raluca Lucacel summarises a systematic review of individually modifiable risk factors to ameliorate cognitive ageing. The study included Mediterranean diet, Tai Chi, Soy isoflavones, B Vitamins and Vitamin D.
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This Cochrane review looked at cryotherapy (ice chips) for preventing oral mucositis in patients with cancer. 14 RCTS involving 1280 patients were included providing evidence that oral cryotherapy leads to large reductions in oral mucositis of all severities in adults receiving 5FU for solid cancers. However there was less confidence confident in the ability of oral cryotherapy to reduce oral mucositis in adults receiving high-dose melphalan before haematopoietic stem cell transplantation (HSCT).
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This Cochrane review only identified 2 RCTs involving a total of 59 patients that show a beneficial effect of systemically administered tranexamic acid and epsilon aminocaproic acid in preventing postoperative bleeding in people with haemophilia undergoing dental extraction.
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Rachel Upthegrove appraises a recent systematic review of psychosocial suicide prevention for youth, which leaves her calling for better evidence to support investment in universal school-based interventions.
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Five RCTs were included in this Cochrane review comparing crowns with fillings for the management of caries in primary molars. Moderate evidence found crowns reduced the risk of major failure or pain in the long term compared to fillings
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Laura Bennett highlights a recent systematic review, which finds very limited evidence to help inform service responses to people with intellectual disabilities with epilepsy.
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This review looked at the evidence linking carotid atherosclerosis with periodontal disease 15 studies involving 17,330 patients were included. The overall pooled result showed periodontal disease was associated with carotid atherosclerosis, OR=1.27 (95% C; 1.14–1.41; P = 0.001). However, once adjusted for smoking and diabetes mellitus, this reduced to borderline significance OR=1.08 (95% CI; 1.00–1.18; P = 0.05).
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This review looked at the impact of premolar extraction on soft tissue profile in class II division 1 malocclusions. 13 studies were included the majority being retrospective. There is some evidence to suggest an increase in the nasolabial angle but the quality is limited.
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Sarah Knowles summarises an individual patient data meta-analysis, which explores baseline depression severity as a moderator of depression outcomes between CBT and antidepressants.
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