7 small studies are included in this Cochrane review which suggests that adjunctive periodontal therapy helps increase the efficiency of H. pylori eradication. OR = 2.15 (95%CI; 1.47 to 3.14)
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Samei Huda discusses the findings of a recent review into suicidality and aggression during antidepressant treatment. The systematic review and meta-analyses were based on clinical study reports and included some important adverse effects of antidepressants in children and young people.
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8 prospective and 11 retrospective studies were included in this review of wide (≥5 mm) dental implants. Data suggests 5-year survival rates over 92% ( 95%CI; 79.6%- 97.5%).
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This review only identified 5 small studies that provided insufficient evidence to compare outcomes using sodium hypochlorite and chlorhexidine for root canal disinfection. Additional high quality RCTs are required.
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Only 4 small studies at high risk of bias were available for this review of cone-beam computed tomography (CBCT) for diagnosis of vertical root fracture, providing insufficient evidence to suggest that CBCT is a reliable test.
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15 studies involving 1722 patients were included in this Cochrane review update on orthodontic retention. However, there was insufficient high quality evidence to make recommendations on retention procedures.
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Akshay Nair explores the results of a systematic review of cognitive tests for dementia and mild cognitive impairment, which focuses on the MMSE, Mini-Cog, ACE-R and MoCA instruments. Along the way he explains how diagnostic tests work and how sensitivity and specificity are useful measures to get your head around.
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This review of platform-switching of dental implants included 17 RCTs and found that bone loss was lower than in regular platform implants, mean difference = -0.41mm (95%CI; -0.58 to -0.24) with no difference in failure rates RR = 1.10 (95%CI; 0.6–2.02).
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Tracey Roberts appraises a systematic review of group psychotherapies for schizophrenia, which includes group CBT, music therapy, art therapy and social skills training.
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Lisa Burscheidt summarises a recent Cochrane systematic review of Omega-3 fatty acids for depression in adults, which finds a lack of evidence to determine the effects of n-3PUFAs as a treatment for major depressive disorder.
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