Results: 675

For: randomised controlled trial

Small study suggests possible role for low-level laser therapy in treating recurrent oral ulcers

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Recurrent aphthous stomatitis (RAS) is the most common form of oral ulceration. Prevalence rates for the general population vary between 5-60%. Onset generally peaks between the ages of 10-19 an often persists in to adulthood. A wide range of topical and systematic treatments have been utilised including low-level laser therapy. The aim of the study [read the full story…]

CBT is more cost-effective than SSRI alone as treatment for panic disorder

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In addition to its impact on quality of life, panic disorder can have a number of costly consequences such as lost productivity – particularly if also associated with agoraphobia. Cost-effectiveness is therefore an important consideration in choosing the optimal treatment for panic disorder, which might improve value via the cost side of the equation. A recent [read the full story…]

Cost effectiveness of surgery versus root planing in patients with chronic periodontitis

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Both surgical and non-surgical approaches can be used for the treatment of chronic periodontitis. The traditional approach being improving plaque control and non- surgical scaling and root planing (SRP) followed by surgical re-treatment where indicated. The main aim of this study was to compare immediate surgery with SRP in the treatment of advanced periodontal disease [read the full story…]

Targeted mindfulness-based relapse prevention may support long-term outcomes for substance use disorders

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Approximately 10.6% of individuals with Substance Use Disorders (SUD) in the US seek treatment, with 40-60% relapsing within a year (Dept of Health and Human Services, 2008; McLellan et al, 2000). This highlights a real need for substance abuse treatment that focuses on relapse prevention. This blog summarises a recent RCT from JAMA Psychiatry on [read the full story…]

Anorexia Nervosa and Oxytocin: focusing our attention

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Anorexia Nervosa (AN) is a very serious illness with a high morbidity; it is also notoriously difficult to treat. Praise then to researchers investigating innovative treatments that might help. This pair of papers investigating the hormone oxytocin have been widely reported in the popular press, from the BBC to Time magazine and the Daily Mail (link withheld [read the full story…]

Small trial suggests limited short-term benefit from 0.1% pilocarpine mouthwash for xerostomia

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Xerostomia is a subjective sensation of dry mouth, this is a common symptom particularly in older adults and has a variety of causes. Pilocarpine is a cholinergic agonist that non-selectively binds to muscarinic receptors in smooth muscles in the gastrointestinal, urinary and pulmonary systems and stimulates the production of secretions from the salivary and sweat [read the full story…]

Trial found similar outcomes with total and partial caries removal in primary molars

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The aim of this study was to compare 24-month pulp health outcomes of partial caries removal (PCR) and total caries removal (TCR) with composite restoration in primary molars. Children (3–8 years), in good general health and amenable to treatment, with at least one molar with acute, deep carious lesion into dentine were included. The teeth [read the full story…]

Moving to better neighbourhoods: bad for boys, good for girls?

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The link between external influences such as family and neighbourhood experiences and young people’s mental health outcomes has been extensively commented on in the literature. While it is more common for studies to focus on the individual or family level, looking at things from a wider perspective is interesting especially from a public mental health [read the full story…]

New study demonstrates effectiveness of antipsychotic Pimavanserin for Parkinson’s disease psychosis

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When we think of Parkinson’s disease (PD), hallucinations and delusions are probably not the first symptoms that come to mind. And yet, it is estimated that nearly half of all patients with PD experience psychotic symptoms at one time or another. Although deficits in motor function are seen as the hallmark of PD, it is [read the full story…]

Study suggests increased failure risk in root treated teeth with less coronal structure restored with fibre post

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The aim of this study was to assess whether the amount of residual coronal structure and the type of cement used for fibre post luting (self-adhesive cement vs. composite core material) affected the four-year survival of root-filled premolars. Patients requiring endodontic treatment and single-unit crown restoration of premolars were eligible.  Patients were divided into two [read the full story…]