Results: 675

For: randomised controlled trial

Paliperidone Palmitate is no better than Haloperidol Decanoate at preventing relapse or controlling psychotic symptoms

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Alex Langford summarises a relatively large and pragmatic study, which provides firm evidence that the newer antipsychotic, Paliperidone, is no better at preventing relapse or controlling psychotic symptoms than its decades-old comparator, Haloperidol.

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Trial suggests that infiltrating early carious lesions in primary molars is effective

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Despite fails in caries level in recent decades caries is still a significant problem for many children The aim of this study was to compare the effect of infiltration and fissure sealing with fluoride varnish applications. Children aged 5-8 with at least three primary molars with initial lesions on three occlusal surfaces in each child [read the full story…]

Bridging the gap: low intensity collaborative care for patients with recent cardiac events can improve mental health and quality of life

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There are many interfaces in mental health services, such as the one between physical and mental health. Where there are interfaces, there are inevitably gaps for patients to fall through. Consequently opportunities are missed to treat mental health problems in those with physical health problems. There is mounting evidence for the effectiveness of Collaborative Care (CC) [read the full story…]

Study suggests benefits to adjacent teeth from application of fluoride containing fissure sealants

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There is good quality review evidence (Ahovuo-Saloranta et al.  2013) that resin-based fissure sealants are effective at preventing or controlling occlusal caries. The aim of this trial was to assess whether sealing first permanent molars with fluoride releasing compounds reduced the caries increment on the distal surface of the second primary molars. Children with at [read the full story…]

Study suggests that fissure sealants can arrest caries in primary molars

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There is good evidence for the effectiveness of fissure sealants in the prevention of caries (Dental Elf 8th April 2013) and some evidence for its use in the treatment of carious lesions. There is also evidence for the effectiveness of partial rather complete caries removal (Dental Elf 13th Apr – 2014).The aim of this study [read the full story…]

Is telephone peer support for the prevention of postnatal depression worth the cost?

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. Peer support has been a hot topic in the woodland recently. Although there appears to be a lack of evidence to support the clinical effectiveness of peer support interventions for people with severe mental illness, such as bipolar disorder and schizophrenia, it is an approach that is highly valued by many. It might be [read the full story…]

RCT shows CBT is more effective than psychoanalytic psychotherapy for treating bulimia nervosa, but that’s only half the story

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I had actually heard about this Danish study, published recently by Poulsen et al. (2014) in the American Journal of Psychiatry, before it landed in my inbox. The findings are interesting because they highlight the debate surrounding the comparative efficacy of psychological treatments. What is most striking though, is how the study itself challenges the [read the full story…]

Study finds no evidence that replacing missing posterior teeth with removable dental prosthesis decreases risk of TMD pain in patients with shortened dental arches

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Over the last few days we have been looking at various outcomes from a multicenter trial that compared the outcomes for two different treatment options for the shortened dental arch. The aim of this analysis was to assess the impact of missing posterior support on the risk for temporomandibular disorder (TMD) pain. As outlined previously [read the full story…]

Trial found no difference in oral health quality of life outcomes for two approaches to management of the shortened dental arch

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Yesterday we looked at the reported periodontal outcomes from a multicenter trial that compared the outcomes for two different treatment options for the shortened dental arch. Today we are considering the report of the oral health quality of life outcomes (OHRQoL). As outlined previously patients were randomised into two groups; a partial removable dental prosthesis [read the full story…]

Trial found minor deterioration of periodontal status in patients with a partial removable dental prosthesis

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The World Health Organisation has stated that the retention, throughout life, of a functional, aesthetic, natural dentition of not less than 20 teeth and not requiring recourse to prostheses should be the treatment goal for oral health. This is consistent with the concept of the shortened dental arch (SDA) with an intact anterior region and [read the full story…]