Results: 1412

For: meta-analysis

Antidepressants for depression in schizophrenia: when good-enough evidence is good enough

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Carmine Pariante is positive about a recent systematic review and meta-analysis of antidepressants for the treatment of depression in schizophrenia.

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Third molar extraction – does platelet-rich fibrin improve outcomes?

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6 studies were identified for this review of platelet-rich fibrin to improve outcomes after third molar extraction. The studies were small with contradictory findings so further high quality studies are needed.

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Orthodontic space closure – Springs or chains?

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4 RCTs were included in this review of Nickel- titanium closing springs (NiTi-CS) and elastomeric power chains (EPC). The findings suggest there is medium quality evidence that space closure is faster with NiTi-CS.

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Root canal obturation using core-carrier techniques

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19 studies were included in this review of core-carrier obturation techniques in endodontic treatment. Success rates was 83%(95CI; 69-91%) with 24% suffering postoperative pain and 31% having overfilling.

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School dental screening

The review found that adding family-based interventions to school-based interventions may reduce the onset of smoking by 4-25%.

This Cochrane review of school dental screening included 6 RCTs finding insufficient evidence that it improves dental attendance. although personalised referral letters or additional motivation elements probably have the ability to improve dental attendance over the short term.

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Atraumatic Restorative Treatment (ART)

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15 RCTs were included in this Cochrane review of Atraumatic Restorative Treatment (ART) comparing with conventional treatment for managing dental caries lesions in the primary and permanent teeth provided low quality evidence that ART using H-GIC may have a higher risk of restoration failure in primary teeth.

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Taste disturbances- zinc supplements may have some benefit

There are lots of reasons to eat healthily, but for the time being, it's not clear whether good food can help prevent depression

10 RCTs were included in this update of a Cochrane review of interventions for the management of patients with taste disturbances. VEry low quality evidence suggest that zinc supplementation my be beneficial but further high quality research is needed.

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Metal-free fixed dental prosthesis – insufficient evidence to support or refute effectiveness

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Only 9 small RCTs were included in this Cochrane review of metal-free materials for prosthodontic restorations providing insufficient evidence to support or refute the effectiveness of metal-free materials for fixed prosthodontic treatment over metal-ceramic or other type of standard restorations.

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Befriending interventions: are they effective?

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#UCLJournalClub students appraise a systematic review and meta-analysis on the effectiveness of befriending interventions for people with a variety of health conditions including mental illness.

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