This review of combining bone substitutes and enamel matrix derivatives for the management of intrabony periodontal defects only identified 5 small RCTs of limited quality. The addition of EMD to bony substitutes was not seen to be beneficial but the results should be interpreted cautiously due to limitations in the available evidence.
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This review of powered toothbrushes for periodontal health in orthodontic patients included 9 small RCTs. A small statistically significant benefit was noted in short term use.
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Andrew Jones summarises a recent systematic review and meta-analysis of alcohol treatment outcome, which identifies a range of personality traits that are associated with relapse.
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11 RCTs were included in this review of statins as an adjunct to scaling and root planing. The findings suggest improvements in pocket depth and clinical attachment levels with statin use.
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This Cochrane review of drug interventions for pain during orthodontic treatment including 32 RCTs find that analgesics were effective in reducing pain. However, low quality evidence did not show a difference in effectiveness between systemic NSAIDs compared with paracetamol, or topical NSAIDs compared with local anaesthetic.
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This Cochrane review of cytokines and growth factors for preventing oral mucositis in patients having cancer treatment included 35 RCTs finding keratinocyte growth factor beneficial in the prevention of oral mucositis .
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This review of the association between hepatitis C virus (HCV) and oral lichen planus (OLP) identified 19 case-controlled studies. While a 6-fold increase in risk of HCV infection was noted in OLP patients a majority of the studies took place in areas with high endemic HCV rates and there is some concern regarding publication bias and the quality of the available studies.
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This review comparing the treatment effects of lingual and buccal orthodontic appliances only identified 4 small low quality studies. No differences were found however the findings should be interpreted cautiously.
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Elena Marcus presents the findings of an updated Cochrane review on antipsychotic combinations for schizophrenia.
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This review comparing the impact of overdentures with conventional dentures on nutritional status included 8 studies finding no difference in relation to BMI, albumin or vitamin B12 6 months after treatment among the older population
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