Results: 1412

For: meta-analysis

Oral lichen planus: Rate of malignant transformation

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This review of the malignant transformation rate (TR) of oral lichen planus included 21 observational studies the majority of which were retrospective. The overall estimate of TR was 1.4%.

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Silver diamine fluoride for caries prevention in primary teeth

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Four RCTs were included in this review of silver diamine fluoride (SDF) for the prevention of caries in primary teeth. Meta-analysis involving 2 of the studies suggest a preventive fraction = 77.5% (95%CI; 67.8– 87.2%)

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Panic disorder in people with bipolar disorder: very common, but treatment options limited

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Tobias Rowland writes his debut elf blog on a recent systematic review and meta-analysis, which finds that panic disorder is highly prevalent in people with bipolar disorder, but there are very limited treatment options.

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Toothbrushing: fluoride toothpaste needed to reduce caries

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Three RCTs were included in this review of the association between personal oral hygiene and coronal dental caries. The findings suggest that in the absence of fluorides personal oral hygiene did not reduce the incidence of caries.

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Crown lengthening – Are outcomes stable?

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This review to assess if surgical crown lengthening produces stable clinical outcomes only identified 5 small trials all at high risk of bias

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Oral potentially malignant disorders – how common are they?

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This review of the prevalence of oral potentially malignant disorders included 22 observational studies providing a pooled estimate for prevalence of 4.47% (95% CI;2.43-7.08).

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Fixed orthodontic appliances- which type of archwire first?

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This Cochrane review of the effects of initial arch wires for the alignment of teeth with fixed orthodontic appliances includes 12 RCTs and updates a previous review. The review finds moderate quality evidence shows that archwires of coaxial superelastic nickel-titanium (NiTi) can produce greater tooth movement over 12 weeks than arch wires made of single-strand superelastic NiTi.

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The burden of mortality and morbidity carried by marginalised populations

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Noortje Uphoff appraises a systematic review and meta-analysis of morbidity and mortality in homeless individuals, prisoners, sex workers and individuals with substance use disorders in high-income countries.

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Dentine hypersensitivity: Effectiveness of desensitising toothpastes

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This review evaluating the effectiveness of desensitising toothpastes included 53 RCTs. Most agents with the exception of those containing strontium or amorphous calcium phosphate were effective in relieving dentine hypersensitivity compared with negative controls.

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Asking about suicide does not cause harm, in fact it may help

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Pooky Knightsmith considers the benefits and risks of asking research participants about suicide in this important blog, which summarises a recent meta-analysis on the impact of exposure to suicide-related content.

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