Results: 1413

For: meta-analysis

Systematic review highlights a lack of evidence about using antidepressants to treat cancer patients with depression

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Having a life threatening disease such as cancer and undergoing gruelling treatment can have detrimental psychological effects. According to a recent review, for instance, the prevalence of depression among cancer patients is 10.8%, when assessed by a standardised clinical assessment (Ng et al. 2011). The authors of this meta-analysis make the argument that established criteria [read the full story…]

Only low-quality evidence to assess effectiveness of bonding for fixed orthodontic appliances

iStock_000002551343XSmall colourful braces on teeth

Fixed banded orthodontic treatment is commonplace not only amongst children by but increasingly in adults.  Being able to successful bond these brackets to the teeth during treatment is a one factor for successful treatment.   The aim of this review was to compare the effects of different dental etchants and different etching techniques for the bonding [read the full story…]

Identifying risk factors in first episode psychosis: results from two new meta-analyses

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A first episode of psychosis is a higher risk time for acts of self-harm and of violence, and a chance to engage people, modify risk factors and change outcomes. Two related meta-analyses by Large, Neilssen and Challis are presented in a letter in the Australian and New Zealand Journal of Psychiatry.  They summarise two studies [read the full story…]

Cochrane review finds ‘solid’ evidence for CBT for anxiety in young people, but lacks evidence for long-term benefits

Anxiety disorders, such as generalised anxiety disorder (GAD), social anxiety, panic disorder and phobias, are common and affect between 5 – 19% of all children and adolescents (Costello, 2004; as cited in James et al, 2013, pg. 6).  Anxiety problems in childhood or adolescence can disrupt social and educational life, and may persist into adulthood. [read the full story…]

Cutting across diagnostic categories: Does stimulant medication improve ADHD symptoms in children with autism spectrum disorder?

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Until fairly recently, it was thought that autism spectrum disorder (ASD; previously known as PDD or pervasive developmental disorder) and attention deficit hyperactivity disorder (ADHD) were two entirely separate childhood-onset conditions and that they could not both be diagnosed in one individual. Numerous studies in the last decade have shown that, in reality, a number of [read the full story…]

Do antipsychotics cause progressive brain changes in schizophrenia?

People with schizophrenia taking antipsychotics saw a reduction in grey matter

For over 30 years researchers have found that people with a diagnosis of schizophrenia have, on average, differences on brain scans compared to people without.  Not everybody with a diagnosis of schizophrenia will have these differences and it has not yet been possible to use brain scanning as a test to work out whether someone [read the full story…]

#MindfulnessMonday – Mindfulness moderately effective for reducing symptoms of psychosis, though controlled studies less convincing

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Last week, Elly O’Brien blogged about mindfulness-based cognitive therapy (MBCT) for various physical and psychological disorders. Today, another paper from the same authors, looking at the more broadly defined ‘mindfulness interventions’ for psychosis. Elly talked about the use of mindfulness to escape the “emotional quicksand” of negative thoughts, and the authors here again focus on [read the full story…]

Fluorescence-based caries detection methods need more work to establish diagnostic accuracy

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Earlier this week (Dental Elf 15th Oct 2013) we looked at a systematic review that looked at a range of the newer aids for detecting caries.  The aim of this review was to synthesize the findings about the accuracy of fluorescence-based methods in detecting caries lesions on occlusal, approximal and smooth surfaces of both permanent [read the full story…]

#MindfulnessMonday – Mindfulness proves effective in depression and anxiety, but is not superior to traditional CBT

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Last week, Kirsten Lawson blogged about mindfulness-based stress reduction as a treatment for breast cancer.  We have featured a number of blogs on mindfulness in the last couple of years, including a piece about the use of Mindfulness-based cognitive therapy (MBCT). MBCT is recommended by NICE to prevent relapse in people who have already experienced three [read the full story…]

A meta-analysis of cognitive-behavioral therapy for adult depression: the winner takes it all?

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Cognitive-behavioral therapy (CBT) is widely researched and recommended as an evidence-based treatment for adult depression, but despite the strength of research comparing CBT approaches with other forms of care, there are few recent systematic reviews on this topic. Cuijpers and collaborators provide such a review in a recent meta-analysis published in The Canadian Journal of [read the full story…]