Results: 1413

For: meta-analysis

Trying to understand brain networks associated with depression is hampered by how variable the condition is

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At the start of using neuroimaging to try and understand mental health problems, the focus was on a specific area of the brain that might be different.  As the methods have become more sophisticated, the ability to look at how different areas of the brain are linked into functional networks has developed.  Whilst damage to [read the full story…]

Systematic review identifies key parenting factors associated with adolescent depression and anxiety

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Parenting is a tough gig. As a mum of three, I can honestly say that nothing in my everyday professional life comes close to the trials and tribulations of guiding small people through toddlerhood and beyond. Parenting advice comes thick and fast from all corners, most of it unsolicited, some of it anecdotal, much of [read the full story…]

“Everyone’s a winner, all must have prizes!” but which psychotherapy for depression wins, if any?

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Previous meta-analyses in the field of depressive disorders have yielded mixed conclusions about which the most efficacious treatment is.  Within the process of any therapy, there are universal features such as; the therapeutic relationship, rationale for treatment, a patient and therapist belief in treatment, a confidential and respectful space for the patient and so on.  [read the full story…]

Meta-analysis finds that pituitary volume is not affected in people with first episode psychosis or schizophrenia

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* Declaration; I have published articles with two of the authors of this article, including on this topic, and know most of them professionally One influential model of the onset of psychotic disorders such as schizophrenia is the stress-vulnerability model, first put forward by Zubin and Spring in 1977. This model proposes that people at [read the full story…]

No evidence that behavioural therapies are any better than other psychological therapies for depression

Depression is a big problem.  In fact, it’s the third leading cause of disease burden worldwide (WHO, 2004 – as cited in Shinohara et al, 2013) and the largest source of nonfatal disease burden in the world (Ustun, 2004 – as cited in Shinohara et al, 2013).   What’s more, the number of people affected by it [read the full story…]

Review suggests that Cone Beam Computed Tomography may have role in diagnosis of root fractures

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While Computed Tomography (CT) is a well-established diagnostic tool in many areas of medicine it is only since the development of Cone Beam Computed Tomography (CBCT) that is use in dentistry is beginning to be explored.  2012 saw the publication of new European evidence-based guidelines on CBCT for dental and maxillofacial radiology as a result [read the full story…]

Review suggests that disinfection methods could be an adjunct or alternative to antifungal medications in the treatment of denture stomatitis

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Denture stomatitis is relatively common with studies suggesting that it can affect 35-50% of complete denture wearers.  It is characterised by mild inflammation and redness of the oral mucosa and about 90% are associated with Candida.   The aim of this review was compare the efficacy of antifungal therapy with any other alternative methods used for [read the full story…]

Periodontal treatment improved several biomarkers of atherosclerotic disease

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In recent years that has been increasing interest in the associations between periodontal disease and a range of systematic diseases.  Towards the end of last year a joint workshop organized by the European Federation of Periodontology (EFP) and the American Academy of Periodontology (AAP) took place in Spain.  The full papers from that meeting are [read the full story…]

Atomoxetine for adult ADHD: the harms outweigh the benefits, according to new systematic review

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Attention Deficit Hyperactivity Disorder (ADHD) is a developmental neurological condition affecting functioning in a number of domains, but in particular, the ability to focus and concentrate, and regulate activity levels.  This is a common disorder with 2.5-4.0% of adults meeting diagnostic criteria for ADHD (Fayyad et al, 2007), and this condition has significant impact on a persons [read the full story…]

Better together: how collaborative working can improve outcomes for patients with depression and diabetes

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The link between depression and diabetes mellitus (DM) is well established. Around 20% of patients with DM meet diagnostic criteria for depression. The National Institute for Health and Care Excellence (NICE) issued guidance impressing the importance of diagnosing and treating depression in long-term conditions such as DM (NICE, 2009). However, depression in the presence of [read the full story…]