Omega-3 fatty acids for depression: Cochrane find insufficient evidence to support use

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Lisa Burscheidt summarises a recent Cochrane systematic review of Omega-3 fatty acids for depression in adults, which finds a lack of evidence to determine the effects of n-3PUFAs as a treatment for major depressive disorder.

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Lamotrigine, quetiapine and folic acid for bipolar depression: the CEQUEL trial

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Michael Ostacher considers the findings of the CEQUEL trial, which asks: Does lamotrigine treat bipolar depression when added to quetiapine, and does adding folic acid help any more?

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#SafeStaffing Mental health nursing on inpatient wards

We need validated assessments of depression.

John Baker looks at the implications of the leaked NICE review on #SafeStaffing for Nursing in Inpatient Mental Health Settings, which was recently uncovered by HSJ journalist Shaun Lintern.

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Are Internet interventions cost-effective for mental health?

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Chris Sampson looks at a systematic review of the economics of Internet interventions for common mental health problems such as depression and anxiety.

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No sexual health history please, we’re British!

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Kirsten Lawson presents the results of a systematic review of observational cross-sectional studies, which looks at the worldwide prevalence of HIV, hepatitis B and hepatitis C in people with severe mental illness.

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Medication for cognitive impairment in traumatic brain injury: little evidence to support its use

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Eleanor Kennedy summarises a recent Cochrane review of pharmacotherapy for chronic cognitive impairment in traumatic brain injury, which finds insufficient evidence to support its use.

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Lithium for schizophrenia: Cochrane find lack of evidence to support its use

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Raphael Underwood presents a new Cochrane review of lithium for schizophrenia, which assesses the use of lithium as a monotherapy and also in combination with antipsychotics.

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Psychotic-like experiences associated with self-harm, according to new systematic review, but further research is needed

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Katrina Witt critiques a recent systematic review of psychotic-like experiences and the risk of self-harm and suicide in the general population.

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Microglial activity in psychosis and schizophrenia

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Samei Huda summarises a small PET brain imaging study, which looks at two cohorts (Ultra High Risk of Psychosis v Controls and Schizophrenia v Controls) to compare relative levels of microglial activity.

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