This Cochrane review update only identified 1 RCT assessing the difference in survival between bonded and non-bonded amalgam restorations providing insufficient evidence to support or refute a difference.
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Chris Hollis appraises a recent Cochrane systematic review, which casts doubt over the quality of trial evidence and the clinical effectiveness of Methylphenidate for ADHD.
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This review of patient expectations of orthodontic treatment included 13 studies but found that the methodological quality was poor so recommended that future studies are needed based on well constructed theory.
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This review of the adjunctive use of amoxicillin and metronidazole with scaling and root planing for the management of periodontitis found improved clinical outcomes in terms of pocket depth and clinical attachment level with their use.
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Only 5 small studies were included in this review of the long term outcomes of tooth autotransplantation. All but one was retrospective so the findings which suggest 81% survival at 6 years should be interpreted with caution.
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This Cochrane review of bisphosphonate related osteonecrosis of the jaw only identified one small RCT. The trial compared the use of hyperbaric oxygen (HBO) as an adjunct to standard care. While it suggested a benefit for HBO it was under powered and at high riisk of bias
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Rosalyn Nelson summarises a recently updated Cochrane systematic review of statins for dementia prevention, which finds no evidence to support their use.
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Jasmin Wertz summarises a systematic review of the clinical effectiveness and cost-effectiveness of parenting interventions for children with severe attachment problems.
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11 systematic reviews were included in this overview of review of periodontal disease and glycaemic control in diabetics. The primary studies that underlying these systematic reviews have important limitations. Therefore larger higher quality studies are needed.
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This review of irrigants for pulpectomy in primary teeth only identified 7 small RCTs providing little conclusive evidence. More high quality studies are needed.
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