André Tomlin reports on a new network meta-analysis that brings together the best available evidence comparing the efficacy and acceptability of 21 antidepressants for the acute treatment of adults with major depressive disorder.
This groundbreaking review of 522 trials is the largest ever meta-analysis in psychiatry, and finds that antidepressants are more effective than placebo for short-term treatment of acute depression in adults.
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This review of non-pharmacological intervention to reduce mental distress, pain, and analgesic use in adults undergoing dental treatment included 29 RCTs. The findings suggest positive benefits for the interventions examined with no significant differences between the various interventions.
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2 reviews and 2 RCTs were discussed in this review of the effect of antibiotics on postoperative infections in orthognathic surgery. There is a lack ofclarity on the preferred antibiotic and the optimal duration of administration.
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Inês Pote publishes her debut elf blog about a recent systematic review on the effectiveness of psychological and/or educational interventions in the prevention of anxiety.
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In his debut blog Kenny Strain considers a new review which compares the working times for digital versus conventional impressions as well as patient centered outcomes. The review suggest a patient preference for the digital approach.
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20 RCTs involving a total of 720 patients were included in this review of antiseptic oral sprays in the control of dental plaque and gingivitis. The findings suggest then can reduce plaque levels in the short term.
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This review of amoxicillin & metronidazole as an adjunct to non-surgical periodontal treatment included 18 trials . A small benefit was seen with antibiotic use but no clinically meaningful difference between different doses or duration of amoxicillin-plus-metronidazole at 3 months post-treatment.
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17 studies (11 RCTs) were included in this review of occlusal schemes for complete dentures suggesting that bilateral balanced occlusion does not confer better quality of life/satisfaction or masticatory performance and muscle activity.
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7 small RCTs that majority of cross-over design were included in this review of phytotherapy as an adjunct to scaling and root planing for chronic periodontitis. While the findings suggest a benefit these should be viewed with caution until results from larger high quality studies are available.
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20 RCTs were included in this review of low level laser therapy (LLLT) for orthodontic pain. While the findings suggest a benefit a majority of the studies were at high risk of bias so the findings should be interpreted cautiously.
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