29 mainly retrospective studies were included in this review of conservative management approaches for odontogenic keratocysts. While the findings suggest use of decompression followed by enucleation data for recurrence were lower than those found in previous reviews of the topic. High quality prospective studies are needed.
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Students and Teachers from the King’s College London PNoMH Distance Learning MSc summarise a major new meta-analysis that brings together the last 60 years of placebo-controlled antipsychotic drug trials in acute schizophrenia.
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52 studies were identified for this review of the effect of extraction or non-extraction fixed orthodontic treatment of soft tissue profiles . However they were mainly poor quality retrospective studies providing very low quality evidence suggesting that tooth extractions might be associated with differences in the soft tissue profile compared to non-extraction treatment.
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This update of a 2016 Cochrane Oral Health Group review of interventions for post extraction bleeding was unable to identify any published or ongoing trials assessing interventions. Well conducted and reported randomised controlled trials are needed on this question.
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Mark Edwards considers the findings of a new meta-analysis of case-control studies, which looks at the relationship between stressful life events, neglect and abuse with functional neurological disorder.
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Kenny Strain looks at this new review of in-vitro studies examining irrigant activation techniques during root canal treatment. The findings suggest improvemed removal of smear layer and debris. However the impact on clinical outcomes needs further investigation.
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This review of slow-release fluoride devices for caries prevention updates an earlier Cochrane review of the topic. However no new trials have been identified providing insufficient evidence to assess their effectiveness.
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This review of the success rates for autotransplantation of teeth into the anterior maxilla includes 17 studies. While the findings suggest high survival rates there is a lack of agreement of success criteria and the quality of the evidence is low.
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Eloise Stark publishes her debut blog on a recent systematic review, which looks at the effect that treatment for perinatal depression in mothers can have on parenting and child development.
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This review of photodynamic therapy (PDT) for management of symptomatic of oral lichen planus included 5 small studies of limited quality that suggest PDT may be beneficial.
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