Results: 1411

For: meta-analysis

Etching time and bonding of adhesive systems to dentine of primary teeth

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This review the influence of reducing the etching time on the dentine of primary teeth for bonding with etch-and-rinse and self-etching adhesive systems included 8 laboratory studies. The findings suggest that that reductions in acid-etching and primer application did not impact the immediate bond strength.

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Problem solving therapy: is it an effective ingredient for treating depression? #ActiveIngredientsMH

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Karolin Krause summarises a systematic review relating to her own Wellcome Trust funded research on problem solving training for young people with depression.

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Powered toothbrushes and plaque control in orthodontic patients

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Typically, fixed appliance orthodontic treatment can last 18-24 months. As the presence of orthodontic appliance encourages plaque accumulation the maintenance of good oral hygiene is important is prevent adverse oral health outcomes.  The small head sizes of powered toothbrushes are considered to assist effective oral hygiene and have been sown to benefit oral health. The [read the full story…]

Photodynamic therapy for oral lichen planus

Lichen_planusWickham's

This review looked at the efficacy of photodynamic therapy (PDT) for the treatment or oral lichen lplanus (OLP) and compares PDT with steroid therapy. 16 studies were included with the findings suggesting that photodynamic therapy may offer patients with OLP improved pain relief and better efficacy compared to topical corticosteroids.

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Photodynamic therapy as an adjunct to non-surgical periodontal treatment

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This review of the adjunctive effects of lasers or antimicrobial photodynamic therapy (aPDT) to non-surgical periodontal treatment included 17 RCTs. The studies were small and hetrogeneous including just 701 patients in total and of low quality providing very limited evidence.

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Periodontitis: Locally delivered antimicrobials as an adjunct to non-surgical treatment

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This review of of locally delivered antimicrobials as an adjunct to scaling and root planing (SRP) for the non-surgical treatment of patients with periodontitis included 50 RCTs. While the findings indicate statistically significant benefits for probing pocket depth and clinical attachment level (CAL) at 6-9 months and for CAL at 12-60 months their clinical importance can be questioned. In addition most of the studies(47) were considered to be at high risk of bias.

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Antidepressants and psychotherapy for adolescent depression: can they be compared? #ActiveIngredientsMH

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Catherine Harmer summarises a recent network meta-analysis relating to her own Wellcome Trust funded research into antidepressants for young people with anxiety or depression.

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Periodontitis: Systemic antimicrobials as an adjunct to non-surgical treatment

Periodontal disease
Periodontitis

This Cochrane review of the effects of systemic antimicrobials as an adjunct to scaling and root planing (SRP) for the non-surgical treatment of patients with periodontitis identified 45 RCTs. However the evidence is of very low certainty to inform tclinicians and patients if adjunctive antibiotics are beneficial.

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Dental bleaching in-office: What concentration of hydrogen peroxide?

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This review of difference concentrations of hydrogen peroxide for in-office dental bleaching on colour change and bleaching sensitivity included 25 RCTs. The findings indicate that low and medium hydrogen peroxide concentrations had lower risk and intensity of bleaching sensitivity and no difference in colour change efficacy compared with high concentrations.

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Digital pathology: Diagnostic concordance and discordance

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Manas Dave considers this review of the safety and reliability of digital pathology. The review included 24 studies showing high concordance between digital pathology and light microscopy suggesting that digital pathology is a viable alternative to light microscopy.

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